Immobilization of DNA on Polycarbonate Track-etched Membranes--A Novel Support for DNA Microarrays

Fabrication of DNA microarray demands that between ten (diagnostic microarrays) to thousands of probes (research or screening microarrays) are efficiently immobilized to a suitable surface using a suitable chemistry. DNA microarray performance is measured by spot morphology and intensity, background...

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Bibliographic Details
Published in:Indian journal of clinical biochemistry 2022-05, Vol.34 (S1), p.S225
Main Authors: Jain, Bharti, Kulkarni, Savita, Banerjee, Sharmila
Format: Article
Language:English
Subjects:
Analysis
DNA
DNA microarrays
Polycarbonates
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Summary:Fabrication of DNA microarray demands that between ten (diagnostic microarrays) to thousands of probes (research or screening microarrays) are efficiently immobilized to a suitable surface using a suitable chemistry. DNA microarray performance is measured by spot morphology and intensity, background, specificity and sensitivity. To fabricate DNA microarray using polycarbonate track-etched membranes (PC-TEM) as a novel solid support and its comparison to glass and microporous membranes (nylon, nitrocellulose and PVDF).
ISSN:0970-1915