Longitudinal quantitative assessment of coronary atherosclerosis related to normal systolic blood pressure maintenance in the absence of established cardiovascular disease

Background Atherosclerosis‐related adverse events are commonly observed even in conditions with low cardiovascular (CV) risk. Longitudinal data regarding the association of normal systolic blood pressure maintenance (SBPmaintain) with coronary plaque volume changes (PVC) has been limited in adults w...

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Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2022-08, Vol.45 (8), p.873-881
Main Authors: Won, Ki‐Bum, Park, Hyung‐Bok, Heo, Ran, Lee, Byoung Kwon, Lin, Fay Y., Hadamitzky, Martin, Kim, Yong‐Jin, Sung, Ji Min, Conte, Edoardo, Andreini, Daniele, Pontone, Gianluca, Budoff, Matthew J., Gottlieb, Ilan, Chun, Eun Ju, Cademartiri, Filippo, Maffei, Erica, Marques, Hugo, Gonçalves, Pedro de Araújo, Leipsic, Jonathon A., Lee, Sang‐Eun, Shin, Sanghoon, Choi, Jung Hyun, Virmani, Renu, Samady, Habib, Chinnaiyan, Kavitha, Berman, Daniel S., Narula, Jagat, Bax, Jeroen J., Min, James K., Chang, Hyuk‐Jae
Format: Article
Language:English
Subjects:
Atherosclerosis
Blood Pressure
Body mass index
Cardiovascular disease
Cardiovascular Diseases
Cholesterol
Clinical Investigations
Computed Tomography Angiography - methods
Coronary Angiography - methods
coronary artery disease
Coronary Artery Disease - diagnostic imaging
coronary computed tomography angiography
Development and progression
Diabetes
Diagnosis
Disease Progression
Female
Hemoglobin
High density lipoprotein
Humans
Hypertension
Male
Medical imaging
Mortality
Plaque, Atherosclerotic
Risk Factors
systolic blood pressure
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Summary:Background Atherosclerosis‐related adverse events are commonly observed even in conditions with low cardiovascular (CV) risk. Longitudinal data regarding the association of normal systolic blood pressure maintenance (SBPmaintain) with coronary plaque volume changes (PVC) has been limited in adults without traditional CV disease. Hypothesis Normal SBPmaintain is important to attenuate coronary atherosclerosis progression in adults without baseline CV disease. Methods We analyzed 95 adults (56.7 ± 8.5 years; 40.0% men) without baseline CV disease who underwent serial coronary computed tomographic angiography with mean 3.5 years of follow‐up. All participants were divided into two groups of normal SBPmaintain (follow‐up SBP 
ISSN:0160-9289
1932-8737
DOI:10.1002/clc.23870