3D printing of transparent high resolution cerebral aneurysm models by laser stereolithography offers low cost patient specific treatment simulation of aneurysmal coil placement

Purpose: As part of the multicenter cooperation (Aneurysm-Like Synthetic bodies for Testing Endovascular devices in 3D Reality), we evaluated patient specific aneurysm models produced by high resolution Laser Stereolithography (SLA) for simulating coil placement in vitro compared to aneurysm coil pl...

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Bibliographic Details
Published in:Clinical neuroradiology (Munich) 2015-09, Vol.25 (S1), p.24
Main Authors: Knaub, K, Frolich, A, Neumann, A, Eckey, T, Schramm, P, Fiehler, J, Kemmling, A
Format: Article
Language:English
Subjects:
3D printing
Comparative analysis
Intracranial aneurysms
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Summary:Purpose: As part of the multicenter cooperation (Aneurysm-Like Synthetic bodies for Testing Endovascular devices in 3D Reality), we evaluated patient specific aneurysm models produced by high resolution Laser Stereolithography (SLA) for simulating coil placement in vitro compared to aneurysm coil placement in real patients. Methods: 3D rotational angiographic (3D RA) data from 15 aneurysms prior to treatment were processed for printing volumetric models by SLA. Cerebral arterial models were directly printed with transparent photopolymer resin. A simple setup of 3D arterial models connected to PVC tubing with circulation pump (FlowTek) allowed coiling of aneurysms in a real neurological angio suite in an optimal simulated environment. Patient specific 3 models (5 ICA, 4 MCA, 3 basilar, and 3 ACA aneurysms) were filled with coils as used in patients (PC 400 coils, Penumbra, 10 mm x 30 cm to 4 mm x 8 cm; Target coils, Stryker, 4 mm x 10 cm to 2 mm x 2 cm). Feasibility and handling of model coiling was evaluated with respect to real coil embolization. Results: Patient specific aneurysm models with a very high level of anatomical accuracy allowed simulation of coil embolization using equivalent materials (guide wire, distal access- and microcatheter). Coiling of model aneurysm was possible in all 15 cases with the same coil set as used in patients. Coil deployment and final packing density by DSA was similar, however, local packing density at each coil step was different with random coil configuration especially in larger aneurysms and wide neck aneurysms. Conclusions: Rapid prototyping of high resolution cerebral aneurysm models by SLA allows low cost patient specific treatment simulation of aneurysmal coil placement in a realistic environment.
ISSN:1869-1439