Late Diagnosis of Disseminated ISporothrix brasiliensis/I Infection with Bone Marrow Involvement in an HIV-Negative Patient

Sporotrichosis is a fungal disease that causes symptoms similar to those of other infectious and non-infectious diseases, making diagnosis difficult and challenging. Here, we report a case of an HIV-negative patient presenting disseminated sporotrichosis with widespread cutaneous lesions mimicking p...

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Bibliographic Details
Published in:Pathogens (Basel) 2022-12, Vol.11 (12)
Main Authors: Magalhães, Vanessa Caroline Randi, Colombo, Salene Angelini, Freitas, Gustavo José Cota, Moura, Alexandre Sampaio, Vieira, Flávia Cardoso Lopez, Lyon, Ana Cláudia, Azevedo, Maria Isabel, Peres, Nalu Teixeira de Aguiar, Santos, Daniel Assis
Format: Article
Language:English
Subjects:
Bone marrow
Case studies
Diagnosis
Diseases
Sporotrichosis
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Summary:Sporotrichosis is a fungal disease that causes symptoms similar to those of other infectious and non-infectious diseases, making diagnosis difficult and challenging. Here, we report a case of an HIV-negative patient presenting disseminated sporotrichosis with widespread cutaneous lesions mimicking pyoderma gangrenosum, with bone marrow infection, pancytopenia, and hemophagocytic syndrome. However, all the clinical manifestations and a bacterial coinfection delayed the request for a fungal diagnosis. Therefore, sporotrichosis should always be investigated in patients from endemic areas presenting with widespread cutaneous lesions associated with pancytopenia.
ISSN:2076-0817
2076-0817
DOI:10.3390/pathogens11121516