Impact of IStreptococcus agalactiae/I Challenge on Immune Response, Antioxidant Status and Hepatorenal Indices of Nile Tilapia: The Palliative Role of Chitosan White Poplar Nanocapsule

A new insight into the synthesis of the herbal plant (White poplar, Poplus alba) leave extract using chitosan nanocapsule was studied. The in vitro antibacterial activity of chitosan white poplar nanocapsule (CWPNC) against Streptococcus agalactiae (S. agalactiae) was determined. About 120 fish were...

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Bibliographic Details
Published in:Fishes 2023-04, Vol.8 (4)
Main Authors: Abdel Rahman, Afaf N, Ismail, Sameh H, Fouda, Moustafa M. S, Abdelwarith, Abdelwahab A, Younis, Elsayed M, Khalil, Samah S, El-Saber, Mahmoud M, Abdelhamid, Ahmed E, Davies, Simon J, Ibrahim, Rowida E
Format: Article
Language:English
Subjects:
Antibacterial agents
Antioxidants
Aquaculture industry
Atwah, Muhsin Musa Matwalli
Chitin
Environmental aspects
Fishes
Health aspects
Lysozyme
Medicinal plants
Nanoparticles
Poplar
Streptococcus agalactiae
Tilapia
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Summary:A new insight into the synthesis of the herbal plant (White poplar, Poplus alba) leave extract using chitosan nanocapsule was studied. The in vitro antibacterial activity of chitosan white poplar nanocapsule (CWPNC) against Streptococcus agalactiae (S. agalactiae) was determined. About 120 fish were categorized for 7 days into four groups. The first and second (CWPNC) groups were treated with 0 mg/L and 3 mg/L CWPNC in the water, respectively, without being challenged; the first group was a control. The third (S. agalactiae) and fourth (CWPNC + S. agalactiae) groups were treated with 0 and 3 mg/L CWPNC, respectively, and challenged with S. agalactiae (0.5 × 10[sup.7] CFU/mL). The obtained results revealed that CWPNC had an in vitro antibacterial activity against S. agalactiae. Moreover, S. agalactiae infection caused a significant elevation (p < 0.05) in the lipid peroxidation (malondialdehyde) and hepatorenal biomarkers, as well as the lowest significant (p < 0.05) survival rate (33.33%). Moreover, a significant depletion (p < 0.05) in the level of antioxidants (catalase and superoxide dismutase) and the immune indicators (immunoglobulin, lysozyme activity, and complement 3) were the consequences of S. agalactiae infection. Treatment of the infected fish with 3 mg/L CWPNC alleviated these bad circumstances.
ISSN:2410-3888
2410-3888
DOI:10.3390/fishes8040199