IGordonia sputi/I as an Arising Causative Agent of Bacteremia in Immunocompromised Comorbid Dialysis Patients—A Case Report

Improvements in medical care have turned severe diseases into chronic conditions, but often their treatment and the use of medical devices are related to specific complications. Here, we present a clinical case of a long-term dialysis patient who was infected with a rare opportunistic infectious age...

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Bibliographic Details
Published in:Healthcare (Basel) 2023-07, Vol.11 (14)
Main Authors: Vergov, Bozhidar, Angelova, Andreana, Baldzhieva, Alexandra, Kalchev, Yordan, Tsochev, Georgi, Murdjeva, Marianna
Format: Article
Language:English
Subjects:
Bacteremia
Care and treatment
Health aspects
Hemodialysis patients
Immunocompromised host
Inflammation
Prevention
Risk factors
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Summary:Improvements in medical care have turned severe diseases into chronic conditions, but often their treatment and the use of medical devices are related to specific complications. Here, we present a clinical case of a long-term dialysis patient who was infected with a rare opportunistic infectious agent—Gordonia sputi. In recent years, the incidence of Gordonia spp. infections in immunocompromised patients with central venous catheters (CVC) has appeared to rise. The isolation and identification of Gordonia spp. are challenging and require modern techniques. In addition, the treatment is usually persistent and often results in CVC extraction, which is associated with further risk and costs for the patient. We also studied the alterations in the immune status of the patient caused by long-term renal replacement therapy and persistent hepatitis C virus infection. Antibiotic therapy and immunostimulation with Inosine pranobex lead to successful eradication of the infection without the need for CVC replacement.
ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare11142059