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Unusual Case of Pseudomembranous Colitis Presenting as Fever of Unknown Origin Diagnosed by Tc-99m-HMPAO-labeled Leukocytes SPECT/CT/Nedeni Bilinmeyen Ates ile Prezente olan ve Tc-99m-HMPAO Isaretli Lokosit SPECT/BT ile Teshis Edilen Olagan Disi Psodomembranoz Enterokolit Olgusu
The fever of unknown origin (FUO) represents a complex diagnostic challenge due to the wide range of etiologies that could cause it, including neoplastic, infectious, rheumatic/inflammatory, and miscellaneous disorders. Several nuclear medicine techniques have proven to be valuable tools for guiding...
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Published in: | Molecular imaging and radionuclide therapy 2023-06, Vol.32 (2), p.168 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Online Access: | Get full text |
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Summary: | The fever of unknown origin (FUO) represents a complex diagnostic challenge due to the wide range of etiologies that could cause it, including neoplastic, infectious, rheumatic/inflammatory, and miscellaneous disorders. Several nuclear medicine techniques have proven to be valuable tools for guiding etiologic diagnosis in the setting of FUO. One of these is technetium-99m (Tc-99m)-hexamethylpropylene amine oxime (HMPAO)-labeled leukocyte scintigraphy, which is a diagnosis method that allows in most cases the localization and evaluation of the extension of an occult infection. This paper presents an uncommon case of pseudomembranous colitis without diarrhea as etiology of FUO diagnosed by Tc-99m-HMPAO-labeled leukocytes. Keywords: Pseudomembranous colitis, fever of unknown origin, Tc-99m-HMPAO, single-photon emission computed tomography, radionuclide imaging Nedeni bilinmeyen ates (NBA), buna neden olabilecek neoplastik, enfeksiyoz, romatizmal/enflamatuvar ve cesitli bozukluklar dahil olmak uzere cok cesitli etiyolojiler nedeniyle tanisi zor bir durumdur. Birkac nukleer tip tekniginin, NBA'da etiyolojik taniya rehberlik etmek icin degerli araclar oldugu kanitlanmistir. Bunlardan biri, cogu durumda gizli bir enfeksiyonun lokalizasyonuna ve yayiliminin degerlendirilmesine olanak taniyan bir tani yontemi olan teknesyum-99m (Tc-99m)-heksametilpropilen amin oksim (HMPAO) isaretli lokosit sintigrafisidir. Bu yazida, Tc-99m-HMPAO isaretli lokositler ile teshis edilen NBA etiyolojisi olarak diyarenin eslik etmedigi nadir bir psodomembranoz kolit olgusu sunulmaktadir. Anahtar kelimeler: Psodomembranoz kolit, nedeni bilinmeyen ates, Tc-99m-HMPAO, tek foton emisyonlu bilgisayarli tomografi, radyonuklid goruntuleme |
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ISSN: | 2146-1414 |
DOI: | 10.4274/mirt.galenos.2022.59354 |