I-131 Avid Tumor Thrombus in a Case of Poorly Differentiated Thyroid Cancer/Kotu Diferansiye Tiroid Kanseri Olgusunda I-131 Tutan Tumor Trombusu

• Published in: Molecular imaging and radionuclide therapy 2023-06, Vol.32 (2), p.178
• Main Authors: Gill, Sana Munir, Hassan, Aamna, Bashir, Humayun, Shafiq, Waqas
• Format: Article
• Language: English
• Subjects: Blood clot; Case studies; Thrombosis; Thyroid cancer
• ISSN: 2146-1414
• DOI: 10.4274/mirt.galenos.2023.81567

Intravenous tumor extension is a well-recognized phenomenon occurring in various malignancies but is a relatively rare entity in thyroid carcinoma. In patients with poorly differentiated thyroid cancer (pDTC), I-131 avid superior vena cava tumor (SVC) thrombus at initial presentation is infrequent and potential life threatening. Tumor thrombus can form either due to direct vascular extension of the primary mass or by hematogenous spread. Hybrid nuclear imaging can differentiate the two entities, which can impact the treatment plan of the patient. We present images of an interesting case of evolution of SVC thrombus in a 46-year-old woman with diagnosed pDTC over the span of two years. Keywords: I-131 avid tumor thrombus, SPECT/CT, poorly differentiated thyroid cancer Intravenoz tumor yayilimi, cesitli malignitelerde ortaya cikan iyi bilinen bir fenomendir, ancak tiroid karsinomunda nispeten nadir bir antitedir. Kotu diferansiye tiroid kanseri (pDTC) olan hastalarda, baslangicta I-131 avid superior vena cava tumoru (SVC) trombusu nadirdir ve potansiyel olarak yasami tehdit eder. Tumor trombusu, primer kitlenin dogrudan vaskuler yayilimi veya hematojen yayilim nedeniyle olusabilir. Hibrit nukleer goruntuleme, hastanin tedavi planini etkileyebilecek bu iki antiteyi ayirt edebilir. Bu yazida, pDTC tanisi konan 46 yasindaki bir kadinda ilginc bir SVC trombus gelisiminin iki yillik goruntulerini sunuyoruz. Anahtar kelimeler: I-131 tutan tumor trombusu, SPECT/BT, az diferansiye tiroid kanseri