Evaluation of Thyroid Functions and Its Relationship with Disease Status and Mortality in Hospitalized Patients with COVID-19

• Published in: Istanbul medical journal 2023-08, Vol.24 (3), p.272-278
• Main Authors: Bilge, Müge, Kibar Akıllı, Işıl
• Format: Article
• Language: English
• Subjects: Analysis; Coronaviruses; covid-19 pneumonia; Glycoproteins; Hospital patients; Medical research; Medicine, Experimental; Mortality; Patient outcomes; Pituitary hormones; Risk factors; Severe acute respiratory syndrome; Thyroid diseases; thyroid function tests; Thyroid gland; Thyroxine
• ISSN: 2619-9793; 1304-8503; 2148-094X
• DOI: 10.4274/imj.galenos.2023.82783

Introduction:Hospitalized coronavirus disease-2019 (COVID-19) individuals were studied in terms of their thyroid functioning with respect to their disease severity and mortality rate.Methods:The thyroid function tests of 781 in patients with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pneumonia outside the intensive care units were examined as part of this retrospective investigation, which was conducted in a single center. Data from the patients were categorized as deceased or discharged. Based on their diagnostic categories, the patients were grouped according to their thyroid stimulating hormone (TSH), free thyroxine (fT4), and free triiodothyronine (fT3) values. TSH, fT4, and fT3 levels were assessed within 24 h after admission.Results:Of the 781 patients who had COVID-19 of, 726 were discharged and 55 died. When compared to the discharged group, deceased patients exhibited lower than normal TSH and fT3 levels (p