Evaluation of plasma atherogenic index in patients with coronary slow flow phenomenon/Koroner yavas akim fenomeni olan hastalarda plazma aterojenik indeksinin incelenmesi

Purpose: Coronary slow flow phenomenon (CSFP) is considered a precursor of coronary artery disease (CAD) and associated with diffuse atherosclerosis, although its pathophysiology is still unclear. The atherogenic index of plasma (AIP) is associated with high cardiovascular risk. In this study, it is...

Full description

Saved in:
Bibliographic Details
Published in:Pamukkale Medical Journal 2022-07, Vol.15 (3), p.491
Main Authors: Adali, Mehmet Koray, Buber, Ipek, Turkoz, Anil, Til, Aysen
Format: Article
Language:English
Subjects:
Analysis
Angiography
Atherosclerosis
Cardiac patients
Care and treatment
Coronary heart disease
Low density lipoproteins
Medical records
Risk factors
Triglycerides
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page
container_issue 3
container_start_page 491
container_title Pamukkale Medical Journal
container_volume 15
creator Adali, Mehmet Koray
Buber, Ipek
Turkoz, Anil
Til, Aysen
description Purpose: Coronary slow flow phenomenon (CSFP) is considered a precursor of coronary artery disease (CAD) and associated with diffuse atherosclerosis, although its pathophysiology is still unclear. The atherogenic index of plasma (AIP) is associated with high cardiovascular risk. In this study, it is aimed to investigate the relationship between AIP and CSFP. Material and method: Hospital records and coronary angiography (CAG) images of 214 patients with normal coronary arteries (NCA) and CSFP patients who underwent CAG between January 2019 and November 2021 have been retrospectively reviewed. Results: The patients were divided into two groups, CSFP (n=107) and NCA (n=107). The mean age was 59.3 years and 50.9% were male. Other demographic characteristics were similar between the two groups, except for gender distribution, age, frequency of HT, and smoking history. There was no difference in laboratory findings except glomerular filtration rate (GFR), serum creatinine level, LDL-C, HDL-C, non-HDL-C, and triglyceride levels. The AIP value was found high and statistically significant in patients with CSFP (p
doi_str_mv 10.31362/patd.1091410
format article
fullrecord <record><control><sourceid>gale</sourceid><recordid>TN_cdi_gale_infotracmisc_A767773225</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A767773225</galeid><sourcerecordid>A767773225</sourcerecordid><originalsourceid>FETCH-LOGICAL-g675-95eb44a4c3d0041510245da55743ea416991eaacda441b8147c09ae913714d943</originalsourceid><addsrcrecordid>eNptjz1vAjEMhjO0UhFl7B6pM5BckgsZEaIfKlIXdmSSHBfIJehyhdKf1F_ZAB06VJZtyX79PjJCD5SMGGVlMd5DZ0aUKMopuUE9yogaqgljd2iQ0pYQUiguRKF66Ht-AP8BnYsBxwrvPaQGMHS1bePGBqexC8Z-5oqzqbOhS_jouhrr2MYA7QknH4-4Opd9bUNscobx23lrW3yCAyQMO9fg6rp0OHoIuIbUgYfWwJn5dWFm5DYLdhfkLrmQoS5o621obHL36LYCn-zgt_fR8mm-nL0MF-_Pr7PpYrgppRgqYdecA9fMEMKpoKTgwoAQkjMLnJZKUQugDXBO1xPKpSYKrKJMUm4UZ330eLXdgLcrF6rYtaAbl_RqKkspJSsKkVWjf1Q5jG2czr9XLs__HPwAX-yBrw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Evaluation of plasma atherogenic index in patients with coronary slow flow phenomenon/Koroner yavas akim fenomeni olan hastalarda plazma aterojenik indeksinin incelenmesi</title><source>Publicly Available Content Database</source><creator>Adali, Mehmet Koray ; Buber, Ipek ; Turkoz, Anil ; Til, Aysen</creator><creatorcontrib>Adali, Mehmet Koray ; Buber, Ipek ; Turkoz, Anil ; Til, Aysen</creatorcontrib><description>Purpose: Coronary slow flow phenomenon (CSFP) is considered a precursor of coronary artery disease (CAD) and associated with diffuse atherosclerosis, although its pathophysiology is still unclear. The atherogenic index of plasma (AIP) is associated with high cardiovascular risk. In this study, it is aimed to investigate the relationship between AIP and CSFP. Material and method: Hospital records and coronary angiography (CAG) images of 214 patients with normal coronary arteries (NCA) and CSFP patients who underwent CAG between January 2019 and November 2021 have been retrospectively reviewed. Results: The patients were divided into two groups, CSFP (n=107) and NCA (n=107). The mean age was 59.3 years and 50.9% were male. Other demographic characteristics were similar between the two groups, except for gender distribution, age, frequency of HT, and smoking history. There was no difference in laboratory findings except glomerular filtration rate (GFR), serum creatinine level, LDL-C, HDL-C, non-HDL-C, and triglyceride levels. The AIP value was found high and statistically significant in patients with CSFP (p&lt;0.001). In the backward logistic regression analysis, age, smoking, GFR, and AIP were determined as independent predictors for CSFP. In ROC curve analysis, the cut-off value of AIP was found 0.068 in predicting CSFP [sensitivity 72%, specificity 42%, area under the curve (AUC)=0.630; p=0.045]. Conclusion: AIP, a rapid, inexpensive, and applicable index in daily clinical practice for the evaluation of atherogenic dyslipidemia, was found an independent predictor together with the traditional risk factors of age, smoking, LDL-C level, and GFR in patients with CSFP. Key words: Coronary slow flow, atherogenic index of plasma, coronary artery disease. Amac: Koroner yavas akim fenomeni (KYAF), patofizyolojisi halen net olmasa da koroner arter hastaligi (KAH) oncusu ve diffuz ateroskleroz ile iliskili olarak kabul edilmektedir. Plazma aterojenik indeksi (PAI) yuksek kardiyovaskuler risk ile iliskilidir. Bu calismada KYAF ile PAI arasindaki iliskinin arastirilmasi amaclanmistir. Gerec ve yontem: Retrospektif olarak Ocak 2019 ile Kasim 2021 tarihleri arasinda koroner anjiyografi (KAG) uygulanan ve KYAF saptanan hastalar ile normal koroner arterleri (NKA) olan toplam 214 hastanin hastane kayitlari ve KAG goruntuleri incelenmistir. Bulgular: Hastalar KYAF (n=107) ve NKA (n=107) olmak uzere iki gruba ayrildi. Yas ortalamasi 59,3 olup %50,9'u erkekti, iki grup arasinda cinsiyet dagilimi, yas, HT sikligi ve sigara oykusu disinda diger demografik ozellikler benzerdi. Glomeruler filtrasyon hizi (GFH), serum kreatinin duzeyi, LDL-K, HDL-K, non HDL-K ve trigliserid duzeyleri disinda laboratuvar bulgulari arasinda fark yoktu. PAI degeri, KYAF olan hastalarda yuksek ve istatiksel olarak anlamli bulundu (p&lt;0,001). Backward lojistik regresyon analizinde yas, sigara kullanimi, GFH ve PAI, KYAF icin bagimsiz prediktor olarak saptanmistir. ROC egrisi analizinde KYAF'yi ongormede PAI cut-off degeri 0,068 olarak saptanmistir [sensitivite %72, spesifite %42, egri altinda kalan alan (AUC)=0,630; p=0,045]. Sonuc: Aterojenik dislipideminin degerlendirilmesinde hizli, ucuz, gunluk klinik pratikte uygulanabilir bir indeks olan PAI, KYAF olan hastalarda geleneksel risk faktorleri olan yas, sigara kullanimi, LDL-K duzeyi ve GFH ile birlikte bagimsiz prediktor olarak bulunmustur. Anahtar kelimeler: Koroner yavas akim fenomeni, plazma aterojenik indeksi, koroner arter hastaligi.</description><identifier>ISSN: 1309-9833</identifier><identifier>DOI: 10.31362/patd.1091410</identifier><language>eng</language><publisher>Pamukkale University</publisher><subject>Analysis ; Angiography ; Atherosclerosis ; Cardiac patients ; Care and treatment ; Coronary heart disease ; Low density lipoproteins ; Medical records ; Risk factors ; Triglycerides</subject><ispartof>Pamukkale Medical Journal, 2022-07, Vol.15 (3), p.491</ispartof><rights>COPYRIGHT 2022 Pamukkale University</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids></links><search><creatorcontrib>Adali, Mehmet Koray</creatorcontrib><creatorcontrib>Buber, Ipek</creatorcontrib><creatorcontrib>Turkoz, Anil</creatorcontrib><creatorcontrib>Til, Aysen</creatorcontrib><title>Evaluation of plasma atherogenic index in patients with coronary slow flow phenomenon/Koroner yavas akim fenomeni olan hastalarda plazma aterojenik indeksinin incelenmesi</title><title>Pamukkale Medical Journal</title><description>Purpose: Coronary slow flow phenomenon (CSFP) is considered a precursor of coronary artery disease (CAD) and associated with diffuse atherosclerosis, although its pathophysiology is still unclear. The atherogenic index of plasma (AIP) is associated with high cardiovascular risk. In this study, it is aimed to investigate the relationship between AIP and CSFP. Material and method: Hospital records and coronary angiography (CAG) images of 214 patients with normal coronary arteries (NCA) and CSFP patients who underwent CAG between January 2019 and November 2021 have been retrospectively reviewed. Results: The patients were divided into two groups, CSFP (n=107) and NCA (n=107). The mean age was 59.3 years and 50.9% were male. Other demographic characteristics were similar between the two groups, except for gender distribution, age, frequency of HT, and smoking history. There was no difference in laboratory findings except glomerular filtration rate (GFR), serum creatinine level, LDL-C, HDL-C, non-HDL-C, and triglyceride levels. The AIP value was found high and statistically significant in patients with CSFP (p&lt;0.001). In the backward logistic regression analysis, age, smoking, GFR, and AIP were determined as independent predictors for CSFP. In ROC curve analysis, the cut-off value of AIP was found 0.068 in predicting CSFP [sensitivity 72%, specificity 42%, area under the curve (AUC)=0.630; p=0.045]. Conclusion: AIP, a rapid, inexpensive, and applicable index in daily clinical practice for the evaluation of atherogenic dyslipidemia, was found an independent predictor together with the traditional risk factors of age, smoking, LDL-C level, and GFR in patients with CSFP. Key words: Coronary slow flow, atherogenic index of plasma, coronary artery disease. Amac: Koroner yavas akim fenomeni (KYAF), patofizyolojisi halen net olmasa da koroner arter hastaligi (KAH) oncusu ve diffuz ateroskleroz ile iliskili olarak kabul edilmektedir. Plazma aterojenik indeksi (PAI) yuksek kardiyovaskuler risk ile iliskilidir. Bu calismada KYAF ile PAI arasindaki iliskinin arastirilmasi amaclanmistir. Gerec ve yontem: Retrospektif olarak Ocak 2019 ile Kasim 2021 tarihleri arasinda koroner anjiyografi (KAG) uygulanan ve KYAF saptanan hastalar ile normal koroner arterleri (NKA) olan toplam 214 hastanin hastane kayitlari ve KAG goruntuleri incelenmistir. Bulgular: Hastalar KYAF (n=107) ve NKA (n=107) olmak uzere iki gruba ayrildi. Yas ortalamasi 59,3 olup %50,9'u erkekti, iki grup arasinda cinsiyet dagilimi, yas, HT sikligi ve sigara oykusu disinda diger demografik ozellikler benzerdi. Glomeruler filtrasyon hizi (GFH), serum kreatinin duzeyi, LDL-K, HDL-K, non HDL-K ve trigliserid duzeyleri disinda laboratuvar bulgulari arasinda fark yoktu. PAI degeri, KYAF olan hastalarda yuksek ve istatiksel olarak anlamli bulundu (p&lt;0,001). Backward lojistik regresyon analizinde yas, sigara kullanimi, GFH ve PAI, KYAF icin bagimsiz prediktor olarak saptanmistir. ROC egrisi analizinde KYAF'yi ongormede PAI cut-off degeri 0,068 olarak saptanmistir [sensitivite %72, spesifite %42, egri altinda kalan alan (AUC)=0,630; p=0,045]. Sonuc: Aterojenik dislipideminin degerlendirilmesinde hizli, ucuz, gunluk klinik pratikte uygulanabilir bir indeks olan PAI, KYAF olan hastalarda geleneksel risk faktorleri olan yas, sigara kullanimi, LDL-K duzeyi ve GFH ile birlikte bagimsiz prediktor olarak bulunmustur. Anahtar kelimeler: Koroner yavas akim fenomeni, plazma aterojenik indeksi, koroner arter hastaligi.</description><subject>Analysis</subject><subject>Angiography</subject><subject>Atherosclerosis</subject><subject>Cardiac patients</subject><subject>Care and treatment</subject><subject>Coronary heart disease</subject><subject>Low density lipoproteins</subject><subject>Medical records</subject><subject>Risk factors</subject><subject>Triglycerides</subject><issn>1309-9833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptjz1vAjEMhjO0UhFl7B6pM5BckgsZEaIfKlIXdmSSHBfIJehyhdKf1F_ZAB06VJZtyX79PjJCD5SMGGVlMd5DZ0aUKMopuUE9yogaqgljd2iQ0pYQUiguRKF66Ht-AP8BnYsBxwrvPaQGMHS1bePGBqexC8Z-5oqzqbOhS_jouhrr2MYA7QknH4-4Opd9bUNscobx23lrW3yCAyQMO9fg6rp0OHoIuIbUgYfWwJn5dWFm5DYLdhfkLrmQoS5o621obHL36LYCn-zgt_fR8mm-nL0MF-_Pr7PpYrgppRgqYdecA9fMEMKpoKTgwoAQkjMLnJZKUQugDXBO1xPKpSYKrKJMUm4UZ330eLXdgLcrF6rYtaAbl_RqKkspJSsKkVWjf1Q5jG2czr9XLs__HPwAX-yBrw</recordid><startdate>20220701</startdate><enddate>20220701</enddate><creator>Adali, Mehmet Koray</creator><creator>Buber, Ipek</creator><creator>Turkoz, Anil</creator><creator>Til, Aysen</creator><general>Pamukkale University</general><scope/></search><sort><creationdate>20220701</creationdate><title>Evaluation of plasma atherogenic index in patients with coronary slow flow phenomenon/Koroner yavas akim fenomeni olan hastalarda plazma aterojenik indeksinin incelenmesi</title><author>Adali, Mehmet Koray ; Buber, Ipek ; Turkoz, Anil ; Til, Aysen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g675-95eb44a4c3d0041510245da55743ea416991eaacda441b8147c09ae913714d943</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Analysis</topic><topic>Angiography</topic><topic>Atherosclerosis</topic><topic>Cardiac patients</topic><topic>Care and treatment</topic><topic>Coronary heart disease</topic><topic>Low density lipoproteins</topic><topic>Medical records</topic><topic>Risk factors</topic><topic>Triglycerides</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Adali, Mehmet Koray</creatorcontrib><creatorcontrib>Buber, Ipek</creatorcontrib><creatorcontrib>Turkoz, Anil</creatorcontrib><creatorcontrib>Til, Aysen</creatorcontrib><jtitle>Pamukkale Medical Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adali, Mehmet Koray</au><au>Buber, Ipek</au><au>Turkoz, Anil</au><au>Til, Aysen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of plasma atherogenic index in patients with coronary slow flow phenomenon/Koroner yavas akim fenomeni olan hastalarda plazma aterojenik indeksinin incelenmesi</atitle><jtitle>Pamukkale Medical Journal</jtitle><date>2022-07-01</date><risdate>2022</risdate><volume>15</volume><issue>3</issue><spage>491</spage><pages>491-</pages><issn>1309-9833</issn><abstract>Purpose: Coronary slow flow phenomenon (CSFP) is considered a precursor of coronary artery disease (CAD) and associated with diffuse atherosclerosis, although its pathophysiology is still unclear. The atherogenic index of plasma (AIP) is associated with high cardiovascular risk. In this study, it is aimed to investigate the relationship between AIP and CSFP. Material and method: Hospital records and coronary angiography (CAG) images of 214 patients with normal coronary arteries (NCA) and CSFP patients who underwent CAG between January 2019 and November 2021 have been retrospectively reviewed. Results: The patients were divided into two groups, CSFP (n=107) and NCA (n=107). The mean age was 59.3 years and 50.9% were male. Other demographic characteristics were similar between the two groups, except for gender distribution, age, frequency of HT, and smoking history. There was no difference in laboratory findings except glomerular filtration rate (GFR), serum creatinine level, LDL-C, HDL-C, non-HDL-C, and triglyceride levels. The AIP value was found high and statistically significant in patients with CSFP (p&lt;0.001). In the backward logistic regression analysis, age, smoking, GFR, and AIP were determined as independent predictors for CSFP. In ROC curve analysis, the cut-off value of AIP was found 0.068 in predicting CSFP [sensitivity 72%, specificity 42%, area under the curve (AUC)=0.630; p=0.045]. Conclusion: AIP, a rapid, inexpensive, and applicable index in daily clinical practice for the evaluation of atherogenic dyslipidemia, was found an independent predictor together with the traditional risk factors of age, smoking, LDL-C level, and GFR in patients with CSFP. Key words: Coronary slow flow, atherogenic index of plasma, coronary artery disease. Amac: Koroner yavas akim fenomeni (KYAF), patofizyolojisi halen net olmasa da koroner arter hastaligi (KAH) oncusu ve diffuz ateroskleroz ile iliskili olarak kabul edilmektedir. Plazma aterojenik indeksi (PAI) yuksek kardiyovaskuler risk ile iliskilidir. Bu calismada KYAF ile PAI arasindaki iliskinin arastirilmasi amaclanmistir. Gerec ve yontem: Retrospektif olarak Ocak 2019 ile Kasim 2021 tarihleri arasinda koroner anjiyografi (KAG) uygulanan ve KYAF saptanan hastalar ile normal koroner arterleri (NKA) olan toplam 214 hastanin hastane kayitlari ve KAG goruntuleri incelenmistir. Bulgular: Hastalar KYAF (n=107) ve NKA (n=107) olmak uzere iki gruba ayrildi. Yas ortalamasi 59,3 olup %50,9'u erkekti, iki grup arasinda cinsiyet dagilimi, yas, HT sikligi ve sigara oykusu disinda diger demografik ozellikler benzerdi. Glomeruler filtrasyon hizi (GFH), serum kreatinin duzeyi, LDL-K, HDL-K, non HDL-K ve trigliserid duzeyleri disinda laboratuvar bulgulari arasinda fark yoktu. PAI degeri, KYAF olan hastalarda yuksek ve istatiksel olarak anlamli bulundu (p&lt;0,001). Backward lojistik regresyon analizinde yas, sigara kullanimi, GFH ve PAI, KYAF icin bagimsiz prediktor olarak saptanmistir. ROC egrisi analizinde KYAF'yi ongormede PAI cut-off degeri 0,068 olarak saptanmistir [sensitivite %72, spesifite %42, egri altinda kalan alan (AUC)=0,630; p=0,045]. Sonuc: Aterojenik dislipideminin degerlendirilmesinde hizli, ucuz, gunluk klinik pratikte uygulanabilir bir indeks olan PAI, KYAF olan hastalarda geleneksel risk faktorleri olan yas, sigara kullanimi, LDL-K duzeyi ve GFH ile birlikte bagimsiz prediktor olarak bulunmustur. Anahtar kelimeler: Koroner yavas akim fenomeni, plazma aterojenik indeksi, koroner arter hastaligi.</abstract><pub>Pamukkale University</pub><doi>10.31362/patd.1091410</doi></addata></record>
fulltext fulltext
identifier ISSN: 1309-9833
ispartof Pamukkale Medical Journal, 2022-07, Vol.15 (3), p.491
issn 1309-9833
language eng
recordid cdi_gale_infotracmisc_A767773225
source Publicly Available Content Database
subjects Analysis
Angiography
Atherosclerosis
Cardiac patients
Care and treatment
Coronary heart disease
Low density lipoproteins
Medical records
Risk factors
Triglycerides
title Evaluation of plasma atherogenic index in patients with coronary slow flow phenomenon/Koroner yavas akim fenomeni olan hastalarda plazma aterojenik indeksinin incelenmesi
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T21%3A27%3A47IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluation%20of%20plasma%20atherogenic%20index%20in%20patients%20with%20coronary%20slow%20flow%20phenomenon/Koroner%20yavas%20akim%20fenomeni%20olan%20hastalarda%20plazma%20aterojenik%20indeksinin%20incelenmesi&rft.jtitle=Pamukkale%20Medical%20Journal&rft.au=Adali,%20Mehmet%20Koray&rft.date=2022-07-01&rft.volume=15&rft.issue=3&rft.spage=491&rft.pages=491-&rft.issn=1309-9833&rft_id=info:doi/10.31362/patd.1091410&rft_dat=%3Cgale%3EA767773225%3C/gale%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-g675-95eb44a4c3d0041510245da55743ea416991eaacda441b8147c09ae913714d943%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_id=info:pmid/&rft_galeid=A767773225&rfr_iscdi=true