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HEADACHE FACIAL PAIN SECTION Profiling migraine patients according to clinical and psychophysical characteristics: a cluster analysis approach

Aim: This study aims to profile migraine patients according clinical and psychophysical characteristics. Method: In this observational study, two cohorts of migraine patients(episodic/chronic) were included. Cohort-1: ictal/perictal phase; Cohort-2: interictal phase. The following variables were ass...

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Published in:Pain medicine (Malden, Mass.) Mass.), 2023-09, Vol.24 (9), p.1046
Main Authors: Antonio, Stefano Di, Arendt-Nielsen, Lars, Ponzano, Marta, Bovis, Francesca, Torelli, Paola, Finocchi, Cinzia, Castaldo, Matteo
Format: Article
Language:English
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Summary:Aim: This study aims to profile migraine patients according clinical and psychophysical characteristics. Method: In this observational study, two cohorts of migraine patients(episodic/chronic) were included. Cohort-1: ictal/perictal phase; Cohort-2: interictal phase. The following variables were assessed: headache frequency; disability; cervical active range of motion(AROM) in flexion, extension, right/left lateral flexion, right/left rotation; pressure-pain threshold(PPT) over: temporalis, two cervical areas(C1/C4 vertebral segments), and two distal painfree areas(hand/leg). Cluster analysis was performed using the K-means algorithm. Differences across clusters were investigated. Results: Cohort-1: 100 patients were included, and two clusters were identified. Cluster-1.1 (19%), Cluster-1.2 (81%). Cluster 1.1 had a higher percentage of men (P=.037) and higher disability (P= .003) compared to Clusters 1.2. Cluster 1.2 had reduced AROM in flexion, extension, and left/right lateral flexion (P
ISSN:1526-2375
DOI:10.1093/pm/pnad048