Dapsone induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome, sparing leprosy patches as an ‘anatopic’ response: A case report

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is an uncommon systemic adverse drug reaction of dapsone. It is characterised by morbilliform exanthema, fever, peripheral blood eosinophilia and deranged liver enzymes. We report an interesting case of dapsone induced DRESS synd...

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Bibliographic Details
Published in:Leprosy review 2023-12, Vol.94 (4), p.354-357
Main Authors: Hegde, Pallavi, Reddy, Sujitha, Pai, Kanthilatha, Rao, Raghavendra
Format: Article
Language:English
Subjects:
Adverse and side effects
Case studies
Complications and side effects
Dapsone
Drugs
Eosinophilia
Leprosy
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Summary:Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is an uncommon systemic adverse drug reaction of dapsone. It is characterised by morbilliform exanthema, fever, peripheral blood eosinophilia and deranged liver enzymes. We report an interesting case of dapsone induced DRESS syndrome sparing the hypopigmented patches of leprosy. Keywords: Adverse effects, Mycobacterium leprae, dapsone hypersensitivity syndrome, histopathology, India
ISSN:2162-8807
0305-7518
2162-8807
DOI:10.47276/lr.94.4.354