Atypical Presentation of Metastatic Castrate-resistant Prostate Cancer in a Middle Aged African Male with Good Response to Radioligand Therapy/Radyoligand Tedavisine Iyi Yanit Veren Orta Yasli Afrikali Bir Erkekte Metastatik Kastrasyon Direncli Prostat Kanserinin Atipik Prezentasyonu

Prostate cancer typically follows a characteristic pattern of metastatic spread to the pelvic lymph nodes and bone. Atypical patterns of metastasis are rare but have been documented. In African men, this disease tends to follow a more aggressive course, with the possibility of an atypical site of me...

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Bibliographic Details
Published in:Molecular imaging and radionuclide therapy 2024-02, Vol.33 (1), p.57
Main Authors: Evbuomwan, Osayande, Endres, Walter, Tebeila, Tebatso, Engelbrecht, Gerrit
Format: Article
Language:English
Subjects:
Care and treatment
Case studies
Diagnosis
Health aspects
Metastasis
Middle aged men
Patient outcomes
Prostate cancer
Radiotherapy
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Summary:Prostate cancer typically follows a characteristic pattern of metastatic spread to the pelvic lymph nodes and bone. Atypical patterns of metastasis are rare but have been documented. In African men, this disease tends to follow a more aggressive course, with the possibility of an atypical site of metastatic spread. We present a case of a 58-year- old African male with metastatic castrate-resistant prostate cancer who presented with both typical and atypical patterns of metastatic disease detected by a fluorine 18 prostate-specific membrane antigen positron emission tomography/computed tomography scan. This patient also had a good response to radioligand therapy. Keywords: Metastatic castrate-resistant prostate cancer, atypical metastases, [.sup.18]F-PSMA Prostat kanseri tipik olarak pelvik lenf dugumlerine ve kemige metastatik yayilim yapar. Atipik metastaz paterni nadirdir ancak daha once gosterilmistir. Afrikali erkeklerde bu hastalik, atipik metastatik yayilma olasiligiyla birlikte daha agresif bir seyir izleme egilimindedir. Flor 18 prostat spesifik membran antijeni pozitron emisyon tomografisi/bilgisayarli tomografi taramasi ile tespit edilen hem tipik hem de atipik metastatik hastalik paterniyle basvuran, metastatik kastrasyon direncli prostat kanseri olan 58 yasinda Afrikali bir erkek olguyu sunuyoruz. Bu hasta ayni zamanda radyoligand tedavisine de iyi yanit vermistir. Anahtar kelimeler: Metastatik kastrasyon direncli prostat kanseri, atipik metastazlar, [.sup.18]F-PSMA
ISSN:2146-1414
DOI:10.4274/mirt.galenos.2023.13471