Enteral Nutritional Support Combined with Dexmedetomidine in Colorectal Cancer Patients Undergoing Laparoscopic Surgery Helps Preserve Postoperative Cognitive Function and Nutritional Status

This study was performed to investigate the impacts of enteral nutritional support combined with dexmedetomidine on colorectal cancer patients undergoing laparoscopic surgery. Patients undergoing laparoscopic surgery were randomly divided into the control (receiving routine anesthesia and postoperat...

Full description

Saved in:
Bibliographic Details
Published in:Current topics in nutraceuticals research 2024-01, Vol.22 (1), p.16-22
Main Authors: Meng, Zhixiu, Sun, Chuanfeng, Yuan, Fujiang, Gao, Cao, Chen, Yan
Format: Article
Language:English
Subjects:
Anesthesia
Cancer
Cancer patients
Colorectal cancer
Dexmedetomidine
Diet therapy
Health aspects
Killer cells
Laparoscopic surgery
Laparoscopy
Oncology, Experimental
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study was performed to investigate the impacts of enteral nutritional support combined with dexmedetomidine on colorectal cancer patients undergoing laparoscopic surgery. Patients undergoing laparoscopic surgery were randomly divided into the control (receiving routine anesthesia and postoperative parenteral nutrition support) and the experimental (receiving dexmedetomidine and postoperative enteral nutritional support) groups. The scores for restlessness score, sedation, adverse reactions, cognitive function, nutritional indexes, immune function, hemodynamics, and postoperative pain score were compared between the two groups. Relative to the control group, the restlessness score, sedation score, mini-mental state examination score, and visual analog scale score of the experimental group were markedly lower. The levels of CD[3.sup.+], CD[4.sup.+], NK cells, the ratio of CD[4.sup.+] to CD[8.sup.+] and the levels of nutritional indexes were significantly increased in the experimental group. Hemodynamic indexes in the experimental group were significantly lower relative to the control group. In conclusion, enteral nutritional support combined with dexmedetomidine anesthesia can inhibit restlessness in the recovery period, promote nutritional status, have little impact on the cognitive function of patients undergoing laparoscopic colorectal cancer surgery, and have a low incidence of complications. Keywords: Cognitive function, Colorectal cancer, Dexmedetomidine, Enteral nutritional support, Laparoscopic surgery, Nutritional indexes
ISSN:1540-7535
DOI:10.37290/ctnr2641-452X.22:16-22