COMBINED FIRST TRIMESTER SCREENING FOR FETAL DOWN SYNDROME AT THE SPLIT UNIVERSITY HOSPITAL CENTER: A SEVEN-YEAR EXPERIENCE/KOMBINIRANI TEST PROBIRA NA FETALNI DOWNOV SINDROM U KLINICKOM BOLNICKOM CENTRU SPLIT: SEDMOGODISNJE ISKUSTVO

The aim of this study was to present the results and to explore the success of combined screening at the Split University Hospital Center. A cross-sectional retrospective study was performed, including all pregnant women who underwent combined screening at the Split University Hospital Center from 2...

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Bibliographic Details
Published in:Acta clinica Croatica (Tisak) 2023-09, Vol.62 (3), p.539
Main Authors: Jakus, Dora, Roje, Damir, Jakus, Ivana Alujevic, Tandara, Leida, Cepic, Katarina
Format: Article
Language:English
Subjects:
Analysis
Diagnosis
Down syndrome
Medical research
Medicine, Experimental
Methods
Pregnant women
Prenatal diagnosis
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Summary:The aim of this study was to present the results and to explore the success of combined screening at the Split University Hospital Center. A cross-sectional retrospective study was performed, including all pregnant women who underwent combined screening at the Split University Hospital Center from 2011 to 2017. Data were collected from the hospital archives. During the research period, a total of 6898 pregnant women underwent combined screening. With the high risk cut-off value set at 1:250, the sensitivity of combined screening was 81.0% and specificity 96.8% (AUC 0.929, 95% CI 0.859-1.000; p
ISSN:0353-9466
DOI:10.20471/acc.2023.62.03.16