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Silver Nanoparticles for Dental Appliance Fabrication: A Systematic Review and Meta-Analysis of Mechanical Properties

Polymethyl methacrylate (PMMA), widely used in orthodontics and dentures, exhibits suboptimal mechanical properties, including flexural strength (FS), impact strength (IS), and tensile strength (TS), which are critical for ensuring durability, resistance to fracture, and overall functionality of den...

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Published in:International journal of molecular sciences 2024-12, Vol.25 (23)
Main Authors: Galant, Kacper, Turosz, Natalia, Chęcińska, Kamila, Chęciński, Maciej, Cholewa-Kowalska, Katarzyna, Karwan, Sławomir, Chlubek, Dariusz, Sikora, Maciej
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container_issue 23
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container_title International journal of molecular sciences
container_volume 25
creator Galant, Kacper
Turosz, Natalia
Chęcińska, Kamila
Chęciński, Maciej
Cholewa-Kowalska, Katarzyna
Karwan, Sławomir
Chlubek, Dariusz
Sikora, Maciej
description Polymethyl methacrylate (PMMA), widely used in orthodontics and dentures, exhibits suboptimal mechanical properties, including flexural strength (FS), impact strength (IS), and tensile strength (TS), which are critical for ensuring durability, resistance to fracture, and overall functionality of dental appliances. Silver nanoparticles (AgNPs) are a promising filler due to their antimicrobial properties. This pre-registered PRISMA-compliant meta-analysis compared the mechanical properties of PMMA/AgNP composites to pure PMMA, considering mean particle size and concentration. Of 360 records from ACM, BASE, PubMed, and Scopus, 35 studies were included (κ = 0.91), covering 88, 38, and 11 tests on FS, IS, and TS, respectively. FS increased only between 30–70 nm (r = 0.00; ρ = 0.03; R [sup.2] [sub.deg2] = 0.13). IS remained higher for
doi_str_mv 10.3390/ijms252312645
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Silver nanoparticles (AgNPs) are a promising filler due to their antimicrobial properties. This pre-registered PRISMA-compliant meta-analysis compared the mechanical properties of PMMA/AgNP composites to pure PMMA, considering mean particle size and concentration. Of 360 records from ACM, BASE, PubMed, and Scopus, 35 studies were included (κ = 0.91), covering 88, 38, and 11 tests on FS, IS, and TS, respectively. FS increased only between 30–70 nm (r = 0.00; ρ = 0.03; R [sup.2] [sub.deg2] = 0.13). IS remained higher for &lt;80 nm and increased between 15 and 25 nm (r = −0.41; ρ = −0.28; R [sup.2] [sub.deg2] = 0.59). TS favored 55 nm but had limited data (r = −0.24; ρ = 0.63; R [sup.2] [sub.deg2] = 0.99). FS decreased with increasing wt%, showing no discernible trend (r = −0.22; ρ = −0.34). IS increased within 0.0–4.0 wt%, particularly 0.5–2.0 wt% (r = −0.15; ρ = −0.35; R [sup.2] [sub.deg2] = 0.54). TS peaked at 0.5–2.0 wt% (r = −0.20; ρ = −0.24; R [sup.2] [sub.deg2] = 0.91). 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Silver nanoparticles (AgNPs) are a promising filler due to their antimicrobial properties. This pre-registered PRISMA-compliant meta-analysis compared the mechanical properties of PMMA/AgNP composites to pure PMMA, considering mean particle size and concentration. Of 360 records from ACM, BASE, PubMed, and Scopus, 35 studies were included (κ = 0.91), covering 88, 38, and 11 tests on FS, IS, and TS, respectively. FS increased only between 30–70 nm (r = 0.00; ρ = 0.03; R [sup.2] [sub.deg2] = 0.13). IS remained higher for &lt;80 nm and increased between 15 and 25 nm (r = −0.41; ρ = −0.28; R [sup.2] [sub.deg2] = 0.59). TS favored 55 nm but had limited data (r = −0.24; ρ = 0.63; R [sup.2] [sub.deg2] = 0.99). FS decreased with increasing wt%, showing no discernible trend (r = −0.22; ρ = −0.34). IS increased within 0.0–4.0 wt%, particularly 0.5–2.0 wt% (r = −0.15; ρ = −0.35; R [sup.2] [sub.deg2] = 0.54). TS peaked at 0.5–2.0 wt% (r = −0.20; ρ = −0.24; R [sup.2] [sub.deg2] = 0.91). Optimal mechanical properties of PMMA/AgNP likely fall within 15–70 nm mean nanoparticle size and 0.5–4.0 wt% concentration.</abstract><pub>MDPI AG</pub><doi>10.3390/ijms252312645</doi></addata></record>
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subjects Analysis
Mechanical properties
Nanoparticles
Polymethylmethacrylate
Silver
title Silver Nanoparticles for Dental Appliance Fabrication: A Systematic Review and Meta-Analysis of Mechanical Properties
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