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Silver Nanoparticles for Dental Appliance Fabrication: A Systematic Review and Meta-Analysis of Mechanical Properties
Polymethyl methacrylate (PMMA), widely used in orthodontics and dentures, exhibits suboptimal mechanical properties, including flexural strength (FS), impact strength (IS), and tensile strength (TS), which are critical for ensuring durability, resistance to fracture, and overall functionality of den...
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Published in: | International journal of molecular sciences 2024-12, Vol.25 (23) |
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creator | Galant, Kacper Turosz, Natalia Chęcińska, Kamila Chęciński, Maciej Cholewa-Kowalska, Katarzyna Karwan, Sławomir Chlubek, Dariusz Sikora, Maciej |
description | Polymethyl methacrylate (PMMA), widely used in orthodontics and dentures, exhibits suboptimal mechanical properties, including flexural strength (FS), impact strength (IS), and tensile strength (TS), which are critical for ensuring durability, resistance to fracture, and overall functionality of dental appliances. Silver nanoparticles (AgNPs) are a promising filler due to their antimicrobial properties. This pre-registered PRISMA-compliant meta-analysis compared the mechanical properties of PMMA/AgNP composites to pure PMMA, considering mean particle size and concentration. Of 360 records from ACM, BASE, PubMed, and Scopus, 35 studies were included (κ = 0.91), covering 88, 38, and 11 tests on FS, IS, and TS, respectively. FS increased only between 30–70 nm (r = 0.00; ρ = 0.03; R [sup.2] [sub.deg2] = 0.13). IS remained higher for |
doi_str_mv | 10.3390/ijms252312645 |
format | article |
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Silver nanoparticles (AgNPs) are a promising filler due to their antimicrobial properties. This pre-registered PRISMA-compliant meta-analysis compared the mechanical properties of PMMA/AgNP composites to pure PMMA, considering mean particle size and concentration. Of 360 records from ACM, BASE, PubMed, and Scopus, 35 studies were included (κ = 0.91), covering 88, 38, and 11 tests on FS, IS, and TS, respectively. FS increased only between 30–70 nm (r = 0.00; ρ = 0.03; R [sup.2] [sub.deg2] = 0.13). IS remained higher for <80 nm and increased between 15 and 25 nm (r = −0.41; ρ = −0.28; R [sup.2] [sub.deg2] = 0.59). TS favored 55 nm but had limited data (r = −0.24; ρ = 0.63; R [sup.2] [sub.deg2] = 0.99). FS decreased with increasing wt%, showing no discernible trend (r = −0.22; ρ = −0.34). IS increased within 0.0–4.0 wt%, particularly 0.5–2.0 wt% (r = −0.15; ρ = −0.35; R [sup.2] [sub.deg2] = 0.54). TS peaked at 0.5–2.0 wt% (r = −0.20; ρ = −0.24; R [sup.2] [sub.deg2] = 0.91). Optimal mechanical properties of PMMA/AgNP likely fall within 15–70 nm mean nanoparticle size and 0.5–4.0 wt% concentration.</description><identifier>ISSN: 1422-0067</identifier><identifier>DOI: 10.3390/ijms252312645</identifier><language>eng</language><publisher>MDPI AG</publisher><subject>Analysis ; Mechanical properties ; Nanoparticles ; Polymethylmethacrylate ; Silver</subject><ispartof>International journal of molecular sciences, 2024-12, Vol.25 (23)</ispartof><rights>COPYRIGHT 2024 MDPI AG</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Galant, Kacper</creatorcontrib><creatorcontrib>Turosz, Natalia</creatorcontrib><creatorcontrib>Chęcińska, Kamila</creatorcontrib><creatorcontrib>Chęciński, Maciej</creatorcontrib><creatorcontrib>Cholewa-Kowalska, Katarzyna</creatorcontrib><creatorcontrib>Karwan, Sławomir</creatorcontrib><creatorcontrib>Chlubek, Dariusz</creatorcontrib><creatorcontrib>Sikora, Maciej</creatorcontrib><title>Silver Nanoparticles for Dental Appliance Fabrication: A Systematic Review and Meta-Analysis of Mechanical Properties</title><title>International journal of molecular sciences</title><description>Polymethyl methacrylate (PMMA), widely used in orthodontics and dentures, exhibits suboptimal mechanical properties, including flexural strength (FS), impact strength (IS), and tensile strength (TS), which are critical for ensuring durability, resistance to fracture, and overall functionality of dental appliances. Silver nanoparticles (AgNPs) are a promising filler due to their antimicrobial properties. This pre-registered PRISMA-compliant meta-analysis compared the mechanical properties of PMMA/AgNP composites to pure PMMA, considering mean particle size and concentration. Of 360 records from ACM, BASE, PubMed, and Scopus, 35 studies were included (κ = 0.91), covering 88, 38, and 11 tests on FS, IS, and TS, respectively. FS increased only between 30–70 nm (r = 0.00; ρ = 0.03; R [sup.2] [sub.deg2] = 0.13). IS remained higher for <80 nm and increased between 15 and 25 nm (r = −0.41; ρ = −0.28; R [sup.2] [sub.deg2] = 0.59). TS favored 55 nm but had limited data (r = −0.24; ρ = 0.63; R [sup.2] [sub.deg2] = 0.99). FS decreased with increasing wt%, showing no discernible trend (r = −0.22; ρ = −0.34). IS increased within 0.0–4.0 wt%, particularly 0.5–2.0 wt% (r = −0.15; ρ = −0.35; R [sup.2] [sub.deg2] = 0.54). TS peaked at 0.5–2.0 wt% (r = −0.20; ρ = −0.24; R [sup.2] [sub.deg2] = 0.91). Optimal mechanical properties of PMMA/AgNP likely fall within 15–70 nm mean nanoparticle size and 0.5–4.0 wt% concentration.</description><subject>Analysis</subject><subject>Mechanical properties</subject><subject>Nanoparticles</subject><subject>Polymethylmethacrylate</subject><subject>Silver</subject><issn>1422-0067</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid/><recordid>eNptTTtPwzAY9AASpTCyW2JO8SNOGraoUEAqD9Hu1Wfnc3HlOFEcivrvsQQDA7rhdKd7EHLF2UzKit24fRuFEpKLIlcnZMJzITLGivKMnMe4Z0xIoaoJ-Vw7f8CBvkDoehhGZzxGaruB3mEYwdO6772DYJAuQQ_OwOi6cEtruj7GEdskDX3Hg8MvCqGhzzhCVgfwx-gi7WwyzAeE1PP0beh6TBcYL8ipBR_x8penZLO83ywes9Xrw9OiXmW7olQZL6XJMUcDjVCqUEbPmSpzVhhrmTQaQFtezlHLgvFKl0xDLplK0KVRWsspuf6Z3YHHrQu2GwcwrYtmW895VSmeM5VSs39SCQ22znQBrUv-n8I3qdxsEw</recordid><startdate>20241201</startdate><enddate>20241201</enddate><creator>Galant, Kacper</creator><creator>Turosz, Natalia</creator><creator>Chęcińska, Kamila</creator><creator>Chęciński, Maciej</creator><creator>Cholewa-Kowalska, Katarzyna</creator><creator>Karwan, Sławomir</creator><creator>Chlubek, Dariusz</creator><creator>Sikora, Maciej</creator><general>MDPI AG</general><scope/></search><sort><creationdate>20241201</creationdate><title>Silver Nanoparticles for Dental Appliance Fabrication: A Systematic Review and Meta-Analysis of Mechanical Properties</title><author>Galant, Kacper ; Turosz, Natalia ; Chęcińska, Kamila ; Chęciński, Maciej ; Cholewa-Kowalska, Katarzyna ; Karwan, Sławomir ; Chlubek, Dariusz ; Sikora, Maciej</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-g675-173c4e4ecad25565cb8057406cff03cbaabf178eb36019b70ba4305050b7c5bb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Analysis</topic><topic>Mechanical properties</topic><topic>Nanoparticles</topic><topic>Polymethylmethacrylate</topic><topic>Silver</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Galant, Kacper</creatorcontrib><creatorcontrib>Turosz, Natalia</creatorcontrib><creatorcontrib>Chęcińska, Kamila</creatorcontrib><creatorcontrib>Chęciński, Maciej</creatorcontrib><creatorcontrib>Cholewa-Kowalska, Katarzyna</creatorcontrib><creatorcontrib>Karwan, Sławomir</creatorcontrib><creatorcontrib>Chlubek, Dariusz</creatorcontrib><creatorcontrib>Sikora, Maciej</creatorcontrib><jtitle>International journal of molecular sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Galant, Kacper</au><au>Turosz, Natalia</au><au>Chęcińska, Kamila</au><au>Chęciński, Maciej</au><au>Cholewa-Kowalska, Katarzyna</au><au>Karwan, Sławomir</au><au>Chlubek, Dariusz</au><au>Sikora, Maciej</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Silver Nanoparticles for Dental Appliance Fabrication: A Systematic Review and Meta-Analysis of Mechanical Properties</atitle><jtitle>International journal of molecular sciences</jtitle><date>2024-12-01</date><risdate>2024</risdate><volume>25</volume><issue>23</issue><issn>1422-0067</issn><abstract>Polymethyl methacrylate (PMMA), widely used in orthodontics and dentures, exhibits suboptimal mechanical properties, including flexural strength (FS), impact strength (IS), and tensile strength (TS), which are critical for ensuring durability, resistance to fracture, and overall functionality of dental appliances. Silver nanoparticles (AgNPs) are a promising filler due to their antimicrobial properties. This pre-registered PRISMA-compliant meta-analysis compared the mechanical properties of PMMA/AgNP composites to pure PMMA, considering mean particle size and concentration. Of 360 records from ACM, BASE, PubMed, and Scopus, 35 studies were included (κ = 0.91), covering 88, 38, and 11 tests on FS, IS, and TS, respectively. FS increased only between 30–70 nm (r = 0.00; ρ = 0.03; R [sup.2] [sub.deg2] = 0.13). IS remained higher for <80 nm and increased between 15 and 25 nm (r = −0.41; ρ = −0.28; R [sup.2] [sub.deg2] = 0.59). TS favored 55 nm but had limited data (r = −0.24; ρ = 0.63; R [sup.2] [sub.deg2] = 0.99). FS decreased with increasing wt%, showing no discernible trend (r = −0.22; ρ = −0.34). IS increased within 0.0–4.0 wt%, particularly 0.5–2.0 wt% (r = −0.15; ρ = −0.35; R [sup.2] [sub.deg2] = 0.54). TS peaked at 0.5–2.0 wt% (r = −0.20; ρ = −0.24; R [sup.2] [sub.deg2] = 0.91). Optimal mechanical properties of PMMA/AgNP likely fall within 15–70 nm mean nanoparticle size and 0.5–4.0 wt% concentration.</abstract><pub>MDPI AG</pub><doi>10.3390/ijms252312645</doi></addata></record> |
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subjects | Analysis Mechanical properties Nanoparticles Polymethylmethacrylate Silver |
title | Silver Nanoparticles for Dental Appliance Fabrication: A Systematic Review and Meta-Analysis of Mechanical Properties |
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