Biokinetics and assessment of intake of thorium dioxide

The aim of this work was to investigate the biokinetics of thorium dioxide in animals for the purpose of assessing intakes of the compound by workers and the resulting doses. The results imply that measurements of the decay products in the chest or extrapolations from urine analysis data are unlikel...

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Bibliographic Details
Published in:Radiation protection dosimetry 2003-01, Vol.105 (1-4), p.115-118
Main Authors: A. Hodgson, S., N. Stradling, G., Hodgson, A., J. Smith, T., J. Youngman, M., Ansoborlo, E.
Format: Article
Language:English
Subjects:
Absorption
Administration, Inhalation
Air Pollutants, Radioactive - analysis
Animals
Biological and medical sciences
Bronchoalveolar Lavage
Computer Science
Computer Simulation
Female
Humans
Inhalation Exposure - analysis
Injections, Intravenous
Lung - metabolism
Medical sciences
Metabolic Clearance Rate
Models, Biological
Nuclear Experiment
Numerical Analysis
Occupational Exposure - analysis
Physics
Radiation Dosage
Radiometry - methods
Rats
Respiratory System - metabolism
Thorax - metabolism
Thorium Dioxide - administration & dosage
Thorium Dioxide - analysis
Thorium Dioxide - pharmacokinetics
Urinalysis
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Summary:The aim of this work was to investigate the biokinetics of thorium dioxide in animals for the purpose of assessing intakes of the compound by workers and the resulting doses. The results imply that measurements of the decay products in the chest or extrapolations from urine analysis data are unlikely to be of value for doses below 20 mSv. Even higher doses should be interpreted with caution as a consequence of uncertainties in particle size distribution and variations in dietary excretion.
ISSN:0144-8420
1742-3406
DOI:10.1093/oxfordjournals.rpd.a006204