Epicutaneous but Not Oral Immunotherapy Leads to Sustainable GATA-3 Hypermethylation and Foxp3 Hypomethylation in Peanut Sensitized Mice

Rationale Epicutaneous immunotherapy (EPIT) is a safe method for treating food allergies and animal models show that protection is sustainable.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2016-02, Vol.137 (2), p.AB128-AB128
Main Authors: Tost, Jorg, PhD, Mondoulet, Lucie, PhD, Puteaux, Emilie, Busato, Florence, Ligouis, Mélanie, Dhelft, Véronique, Plaquet, Camille, Dupont, Christophe, MD, PhD, Benhamou, Pierre-Henri, MD
Format: Article
Language:English
Subjects:
Allergology
Allergy and Immunology
DNA methylation
Epigenetics
Genetics
Immunology
Immunotherapy
Life Sciences
Spleen
Online Access:Get full text
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Description
Summary:Rationale Epicutaneous immunotherapy (EPIT) is a safe method for treating food allergies and animal models show that protection is sustainable.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.551