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A method for synthesis and functionalization of ultrasmall superparamagnetic covalent carriers based on maghemite and dextran
A new generation of susceptibility contrast agents for MRI and based on maghemite cores covalently bonded to dextran stabilizing macromolecules was investigated. The multistep preparation of these versatile ultrasmall superparamagnetic iron oxides (VUSPIO) consisted of colloidal maghemite synthesis,...
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| Published in: | Journal of magnetism and magnetic materials 2005-05, Vol.293 (1), p.127-134 |
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| Main Authors: | , , |
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| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c461t-c33ba2b010f4b83e4d1e2a9f194cdccbc04313e844d36d3af783d3737df0541d3 |
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| cites | cdi_FETCH-LOGICAL-c461t-c33ba2b010f4b83e4d1e2a9f194cdccbc04313e844d36d3af783d3737df0541d3 |
| container_end_page | 134 |
| container_issue | 1 |
| container_start_page | 127 |
| container_title | Journal of magnetism and magnetic materials |
| container_volume | 293 |
| creator | Mornet, Stéphane Portier, Josik Duguet, Etienne |
| description | A new generation of susceptibility contrast agents for MRI and based on maghemite cores covalently bonded to dextran stabilizing macromolecules was investigated. The multistep preparation of these versatile ultrasmall superparamagnetic iron oxides (VUSPIO) consisted of colloidal maghemite synthesis, surface modification by aminopropylsilane groups, and coupling of partially oxidized dextran via Schiff's bases and secondary amine bonds. The dextran corona might be easily derivatized, e.g. by PEGylation. |
| doi_str_mv | 10.1016/j.jmmm.2005.01.053 |
| format | article |
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Portier, Josik ; Duguet, Etienne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c461t-c33ba2b010f4b83e4d1e2a9f194cdccbc04313e844d36d3af783d3737df0541d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>3-Aminopropyltrimethoxysilane</topic><topic>[formula omitted]-Amino poly(ethylene glycol)</topic><topic>[formula omitted]-Diamino telechelic poly(ethylene glycol)</topic><topic>Chemical Sciences</topic><topic>Condensed matter: electronic structure, electrical, magnetic, and optical properties</topic><topic>Contrast agent</topic><topic>Dextran</topic><topic>Diamagnetism, paramagnetism and superparamagnetism</topic><topic>Exact sciences and technology</topic><topic>Ferrofluid</topic><topic>Infrared spectroscopy</topic><topic>Maghemite</topic><topic>Magnetic liquids</topic><topic>Magnetic properties and materials</topic><topic>Material chemistry</topic><topic>MRI</topic><topic>PEGylation</topic><topic>Photon correlation spectroscopy</topic><topic>Physics</topic><topic>Silanation</topic><topic>Studies of specific magnetic materials</topic><topic>Transmission electron microscopy</topic><topic>USPIO</topic><topic>VUSPIO</topic><topic>Zeta potential</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mornet, Stéphane</creatorcontrib><creatorcontrib>Portier, Josik</creatorcontrib><creatorcontrib>Duguet, Etienne</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Hyper Article en Ligne (HAL)</collection><jtitle>Journal of magnetism and magnetic materials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mornet, Stéphane</au><au>Portier, Josik</au><au>Duguet, Etienne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A method for synthesis and functionalization of ultrasmall superparamagnetic covalent carriers based on maghemite and dextran</atitle><jtitle>Journal of magnetism and magnetic materials</jtitle><date>2005-05-01</date><risdate>2005</risdate><volume>293</volume><issue>1</issue><spage>127</spage><epage>134</epage><pages>127-134</pages><issn>0304-8853</issn><eissn>1873-4766</eissn><coden>JMMMDC</coden><abstract>A new generation of susceptibility contrast agents for MRI and based on maghemite cores covalently bonded to dextran stabilizing macromolecules was investigated. The multistep preparation of these versatile ultrasmall superparamagnetic iron oxides (VUSPIO) consisted of colloidal maghemite synthesis, surface modification by aminopropylsilane groups, and coupling of partially oxidized dextran via Schiff's bases and secondary amine bonds. The dextran corona might be easily derivatized, e.g. by PEGylation.</abstract><cop>Amsterdam</cop><pub>Elsevier B.V</pub><doi>10.1016/j.jmmm.2005.01.053</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-0675-5987</orcidid><orcidid>https://orcid.org/0000-0002-1115-5812</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0304-8853 |
| ispartof | Journal of magnetism and magnetic materials, 2005-05, Vol.293 (1), p.127-134 |
| issn | 0304-8853 1873-4766 |
| language | eng |
| recordid | cdi_hal_primary_oai_HAL_hal_00022639v1 |
| source | ScienceDirect Journals |
| subjects | 3-Aminopropyltrimethoxysilane [formula omitted]-Amino poly(ethylene glycol) [formula omitted]-Diamino telechelic poly(ethylene glycol) Chemical Sciences Condensed matter: electronic structure, electrical, magnetic, and optical properties Contrast agent Dextran Diamagnetism, paramagnetism and superparamagnetism Exact sciences and technology Ferrofluid Infrared spectroscopy Maghemite Magnetic liquids Magnetic properties and materials Material chemistry MRI PEGylation Photon correlation spectroscopy Physics Silanation Studies of specific magnetic materials Transmission electron microscopy USPIO VUSPIO Zeta potential |
| title | A method for synthesis and functionalization of ultrasmall superparamagnetic covalent carriers based on maghemite and dextran |
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