Effects of structural modification on gene transfection and self-assembling properties of amphiphilic dendrimers

A library of novel amphiphilic, self-assembling dendrimers was designed and synthesised to evaluate the effects of structural changes on transfection efficiency.

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Bibliographic Details
Published in:Organic & biomolecular chemistry 2006-01, Vol.4 (5), p.766-769
Main Authors: Guillot, Marine, Eisler, Sara, Weller, Kathrin, Merkle, Hans P, Gallani, Jean-Louis, Diederich, François
Format: Article
Language:English
Subjects:
Dendrimers
Genetic Vectors - chemistry
Genetic Vectors - genetics
Green Fluorescent Proteins - genetics
Green Fluorescent Proteins - metabolism
HeLa Cells
Humans
Liposomes - chemistry
Polyamines - chemistry
Structure-Activity Relationship
Transfection - methods
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Description
Summary:A library of novel amphiphilic, self-assembling dendrimers was designed and synthesised to evaluate the effects of structural changes on transfection efficiency.
ISSN:1477-0520
1477-0539
DOI:10.1039/b518174g