Development of the zebrafish lateral line

The lateral line system is simple (comprising six cell types), its sense organs form according to a defined and reproducible pattern, and its neurons are easily visualized. In the zebrafish, these advantages can be combined with a wealth of genetic tools, making this system ideally suited to a combi...

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Bibliographic Details
Published in:Current opinion in neurobiology 2004-02, Vol.14 (1), p.67-73
Main Authors: Ghysen, Alain, Dambly-Chaudière, Christine
Format: Article
Language:English
Subjects:
Animals
Cell Movement
Cell Movement - physiology
Development Biology
Embryonic Induction
Embryonic Induction - physiology
Functional Laterality
Functional Laterality - physiology
Life Sciences
Nervous System
Nervous System - cytology
Nervous System - embryology
Nervous System - growth & development
Sense Organs
Sense Organs - cytology
Sense Organs - embryology
Sense Organs - growth & development
Zebrafish
Zebrafish - embryology
Zebrafish - growth & development
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Summary:The lateral line system is simple (comprising six cell types), its sense organs form according to a defined and reproducible pattern, and its neurons are easily visualized. In the zebrafish, these advantages can be combined with a wealth of genetic tools, making this system ideally suited to a combined molecular, cellular and genetic analysis. Recent progress has taken advantage of these various qualities to elucidate the mechanism that drives the migration from head to tail of the sense organ precursor cells, and to approach the questions surrounding axonal guidance and target recognition.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2004.01.012