Effect of a probiotics supplementation on respiratory infections and immune and hormonal parameters during intense military training

This study examined the effect of a probiotics supplementation on respiratory tract infection (RTI) and immune and hormonal changes during the French Commando training (3-week training followed by a 5-day combat course). Cadets (21 +/- 0.4 years) received either a probiotics (n = 24) or a placebo (n...

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Bibliographic Details
Published in:Military medicine 2007-09, Vol.172 (9), p.1006-1011
Main Authors: Tiollier, Eve, Chennaoui, Mounir, Gomez-Merino, Danielle, Drogou, Catherine, Filaire, Edith, Guezennec, Charles Yannick
Format: Article
Language:English
Subjects:
Administration, Oral
Adult
Dairy products
Dietary Supplements
Dose-Response Relationship, Drug
Double-Blind Method
Fluorescent Antibody Technique
Follow-Up Studies
Hormones - blood
Humans
Immunity, Cellular - drug effects
Immunoglobulin A - metabolism
Immunoglobulins
Infections
Lymphocytes - immunology
Male
Military Personnel - education
Military training
Milk
Probiotics
Probiotics - administration & dosage
Probiotics - therapeutic use
Respiratory Tract Infections - immunology
Respiratory Tract Infections - metabolism
Respiratory Tract Infections - prevention & control
Saliva - metabolism
Treatment Outcome
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Summary:This study examined the effect of a probiotics supplementation on respiratory tract infection (RTI) and immune and hormonal changes during the French Commando training (3-week training followed by a 5-day combat course). Cadets (21 +/- 0.4 years) received either a probiotics (n = 24) or a placebo (n = 23) supplementation over the training period. We found no difference in the RTI incidence between groups but a significantly greater proportion of rhinopharyngitis in the probiotic group (p < 0.05). Among immune parameters, the major finding was an immunoglobulin A decrease after the combat course only in the placebo group (p < 0.01), but the difference between the two groups was not significant. A greater increase in dehydroepiandrostane sulfate was observed in the probiotics group after the combat course (p < 0.05). This study suggested that the benefits of a probiotics supplementation in a multistressor environment relied mainly on its capacity to prevent the infection to spread throughout the respiratory tract.
ISSN:0026-4075
1930-613X
DOI:10.7205/MILMED.172.9.1006