Nanodoublers as deep imaging markers for multi-photon microscopy

We demonstrate the possibility to excite second-harmonic (SH) active Fe(IO(3))(3) nanocrystals with two distinct laser sources at 800 and 1550 nm, and we show, by a complementary experimental and numerical study, how the wavelength flexibility inherent to non-phase-matched SH nanoparticles can be ef...

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Bibliographic Details
Published in:Optics express 2009-08, Vol.17 (17), p.15342-15349
Main Authors: Extermann, Jerome, Bonacina, Luigi, Cuña, Enrique, Kasparian, Christelle, Mugnier, Yannick, Feurer, Thomas, Wolf, Jean-Pierre
Format: Article
Language:English
Subjects:
Animals
Computer Simulation
Iron - chemistry
Lasers
Mice
Microscopy - methods
Microscopy, Fluorescence, Multiphoton - methods
Monte Carlo Method
Nanoparticles - chemistry
Nanotechnology - methods
Nephelometry and Turbidimetry - methods
Optics
Optics and Photonics
Photons
Physics
Polystyrenes - chemistry
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Summary:We demonstrate the possibility to excite second-harmonic (SH) active Fe(IO(3))(3) nanocrystals with two distinct laser sources at 800 and 1550 nm, and we show, by a complementary experimental and numerical study, how the wavelength flexibility inherent to non-phase-matched SH nanoparticles can be efficiently exploited to increase imaging penetration depth of markers embedded in biological samples.
ISSN:1094-4087
1094-4087
DOI:10.1364/OE.17.015342