1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD) an efficient homogeneous catalyst for aldol condensation reactions. Study of the catalyst recovery and reusability using CO2

In this work it was shown that TBD (1,5,7-triazabicyclo[4.4.0]dec-5-ene), a cheap and commercially available guanidine base, efficiently catalyzes aldol condensation reactions yielding interesting products for pharmacological and fragrance industries. This methodology works under solvent-less condit...

Full description

Saved in:
Bibliographic Details
Published in:Tetrahedron letters 2011-01, Vol.52 (3), p.385-387
Main Authors: Cota, Iuliana, Medina, Francisco, Sueiras, Jesús E., Tichit, Didier
Format: Article
Language:English
Subjects:
Aldol condensations
Base catalysis
Catalysis
Chemical Sciences
CO2 fixation
Material chemistry
TBD
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this work it was shown that TBD (1,5,7-triazabicyclo[4.4.0]dec-5-ene), a cheap and commercially available guanidine base, efficiently catalyzes aldol condensation reactions yielding interesting products for pharmacological and fragrance industries. This methodology works under solvent-less conditions and affords with very good conversions the corresponding products. Moreover, a simple and effective separation protocol using the CO2 fixation was employed. The catalyst could be recovered and re-used for three consecutive runs without significant loss of activity.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2010.11.032