Multicomponent reactions and ionic liquids: a perfect synergy for eco-compatible heterocyclic synthesis

The efficiency of a chemical synthesis can be nowadays measured, not only by parameters like selectivity and overall yield, but also by its raw material, time, human resources and energy requirements, as well as the toxicity and hazard of the chemicals and the protocols involved. The development of...

Full description

Saved in:
Bibliographic Details
Published in:Chemical Society reviews 2011-01, Vol.4 (3), p.1347-1357
Main Authors: Isambert, Nicolas, Duque, Maria del Mar Sanchez, Plaquevent, Jean-Christophe, Génisson, Yves, Rodriguez, Jean, Constantieux, Thierry
Format: Article
Language:English
Subjects:
Chemical Sciences
Organic chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The efficiency of a chemical synthesis can be nowadays measured, not only by parameters like selectivity and overall yield, but also by its raw material, time, human resources and energy requirements, as well as the toxicity and hazard of the chemicals and the protocols involved. The development of multicomponent reactions (MCRs) in the presence of task-specific ionic liquids (ILs), used not only as environmentally benign reaction media, but also as catalysts, is a new approach that meet with the requirements of sustainable chemistry. The aim of this tutorial review is to highlight the synergistic effect of the combined use of MCRs and ILs for the development of new eco-compatible methodologies for heterocyclic chemistry. This tutorial review highlights the synergistic effect of the combined use of MCRs and Ils for the development of new eco-compatible methodologies for heterocyclic chemistry.
ISSN:0306-0012
1460-4744
DOI:10.1039/c0cs00013b