Can voronoi diagram model cell geometries in early sea-urchin embryogenesis?

We test the hypothesis that cell membranes in early sea- urchin embryos can be modeled as a Voronoi diagram from nuclei centers. In order to obtain a model of the cell geometry against which to test our Voronoi model hypothesis, we developed a viscous watershed framework that allows segmenting 3D im...

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Bibliographic Details
Main Authors: Luengo-Oroz, M.A., Duloquin, L., Castro, C., Savy, T., Faure, E., Lombardot, B., Bourgine, R., Peyrieras, N., Santos, A.
Format: Conference Proceeding
Language:English
Subjects:
biological cells
Biomembranes
Cells (biology)
Embryo
Geometrical optics
Geometry
Image segmentation
Laser modes
Life Sciences
Microscopy
morphological operations
Neurons and Cognition
Solid modeling
Testing
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Summary:We test the hypothesis that cell membranes in early sea- urchin embryos can be modeled as a Voronoi diagram from nuclei centers. In order to obtain a model of the cell geometry against which to test our Voronoi model hypothesis, we developed a viscous watershed framework that allows segmenting 3D images of living sea-urchin embryos obtained by biphoton laser scanning microscopy. Measurements of the differences between segmented cells and the Voronoi model, show an interesting high correlation that can serve for developing more accurate methods of segmentation and modelling cell geometries.
ISSN:1945-7928
1945-8452
DOI:10.1109/ISBI.2008.4541043