Chemically modified polysulfones for molecular imprinting. Synthesis and complexation with a fluorescent model template

Polysulfone (PSU) was chemically modified to prepare new molecular imprinted membranes (MIMs). Several amounts of amine and sulfonyl groups were introduced into the PSU chemical structure in order to create interactions with acid or base templates, such as biomolecules or biomacromolecules. A fluore...

Full description

Saved in:
Bibliographic Details
Published in:Reactive & functional polymers 2013-03, Vol.73 (3), p.531-539
Main Authors: Kébir, Nasreddine, Sabathié, Nathalie, Fournier-Noël, Clara, Fery-Forgues, Suzanne, Lahitte, Jean-François, Rémigy, Jean-Christophe
Format: Article
Language:English
Subjects:
Applied sciences
Chemical modifications
Chemical reactions and properties
Chemical Sciences
Exact sciences and technology
MIM
MIP
Molecular imprinting
Organic polymers
Physicochemistry of polymers
Polymers
Polysulfone
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Polysulfone (PSU) was chemically modified to prepare new molecular imprinted membranes (MIMs). Several amounts of amine and sulfonyl groups were introduced into the PSU chemical structure in order to create interactions with acid or base templates, such as biomolecules or biomacromolecules. A fluorescent dye, Acridine Orange base (AO), was used as a model template and its complexation with the prepared PSUs was monitored by spectroscopic techniques. This study showed an absence of complexation with the native PSU and a strong complexation with the aminated and the sulfonated PSUs. Partially allylated PSU bearing amine or sulfonyl groups were also synthesized. These compounds are expected to be used as precursors for designing new crosslinked molecular imprinting membranes (MIMs), exhibiting high stability of the template memory.
ISSN:1381-5148
DOI:10.1016/j.reactfunctpolym.2012.12.003