Pinwheel-dipole configuration in cat early visual cortex

• Published in: NeuroImage (Orlando, Fla.) Fla.), 2016-03, Vol.128, p.63-73
• Main Authors: Ribot, Jérôme, Romagnoni, Alberto, Milleret, Chantal, Bennequin, Daniel, Touboul, Jonathan
• Format: Article
• Language: English
• Subjects: Adaptation; Animals; Brain Mapping - methods; Cats; Cortical maps; Dipole; Experiments; Hypotheses; Image Processing, Computer-Assisted; Localization; Mathematical models; Mathematics; Optical Imaging; Optics; Orientation; Photic Stimulation; Probability; Respiration; Singularities; Spatial frequency; Studies; Visual Cortex - anatomy & histology; Visual Cortex - physiology; Visual perception
• ISSN: 1053-8119; 1095-9572
• DOI: 10.1016/j.neuroimage.2015.12.022

In the early visual cortex, information is processed within functional maps whose layouts are thought to underlie visual perception. However, the precise organization of these functional maps as well as their interrelationships remain unsettled. Here, we show that spatial frequency representation in cat early visual cortex exhibits singularities around which the map organizes like an electric dipole potential. These singularities are precisely co-located with singularities of the orientation map: the pinwheel centers. To show this, we used high resolution intrinsic optical imaging in cat areas 17 and 18. First, we show that a majority of pinwheel centers exhibit in their neighborhood both semi-global maximum and minimum in the spatial frequency map (i.e. extreme values of the spatial frequency in a hypercolumn). This contradicts pioneering studies suggesting that pinwheel centers are placed at the locus of a single spatial frequency extremum. Based on an analogy with electromagnetism, we proposed a mathematical model for a dipolar structure, accurately fitting optical imaging data. We conclude that a majority of orientation pinwheel centers form spatial frequency dipoles in cat early visual cortex. Given the functional specificities of neurons at singularities in the visual cortex, it is argued that the dipolar organization of spatial frequency around pinwheel centers could be fundamental for visual processing. •Spatial frequency (SF) and orientation (OR) maps are recorded in cat visual cortex.•Near OR singularities, the two SF semi-global extrema are represented.•A geometrical description shows that SF is represented as a dipole.•Pinwheel-dipole singularities argue against uniform coverage in felines.