Efficacy of Pre-Hospital Use of Glycoprotein IIb/IIIa Inhibitors in ST-Segment Elevation Myocardial Infarction Before Mechanical Reperfusion in a Rapid-Transfer Network (from the Acute Myocardial Infarction Registry of Brittany)

Previous studies investigating prehospital use of glycoprotein IIb/IIIa inhibitors (GPIs) in patients with ST-segment elevation myocardial infarction reached conflicting conclusions. The benefit of this strategy in addition to in-ambulance loading of dual-antiplatelet therapy remains controversial....

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Bibliographic Details
Published in:The American journal of cardiology 2014-07, Vol.114 (2), p.214-223
Main Authors: Auffret, Vincent, MD, Oger, Emmanuel, MD PhD, Leurent, Guillaume, MD, Filippi, Emmanuelle, MD, Coudert, Isabelle, MD, Hacot, Jean Philippe, MD, Castellant, Philippe, MD, Rialan, Antoine, MD, Delaunay, Régis, MD, Rouault, Gilles, MD, Druelles, Philippe, MD, Boulanger, Bertrand, MD, Treuil, Josiane, MD, Avez, Bertrand, MD, Bedossa, Marc, MD, Boulmier, Dominique, MD, Le Guellec, Marielle, MSc, Le Breton, Hervé, MD, PhD
Format: Article
Language:English
Subjects:
Ambulances
Angina pectoris
Angioplasty
Anterior Wall Myocardial Infarction - diagnostic imaging
Anterior Wall Myocardial Infarction - drug therapy
Anterior Wall Myocardial Infarction - physiopathology
Cardiology and cardiovascular system
Cardiovascular
Coronary Angiography
Dose-Response Relationship, Drug
Drug dosages
Electrocardiography
Emergency Medical Services - methods
Female
Hard disks
Heart attacks
Human health and pathology
Humans
Life Sciences
Male
Medical imaging
Middle Aged
Molecular weight
Mortality
Myocardial Reperfusion - methods
Outpatients
Pain
Peptides - administration & dosage
Platelet Aggregation Inhibitors - administration & dosage
Platelet Glycoprotein GPIIb-IIIa Complex - antagonists & inhibitors
Registries
Regression analysis
Thrombolytic Therapy - methods
Time Factors
Treatment Outcome
Variables
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Description
Summary:Previous studies investigating prehospital use of glycoprotein IIb/IIIa inhibitors (GPIs) in patients with ST-segment elevation myocardial infarction reached conflicting conclusions. The benefit of this strategy in addition to in-ambulance loading of dual-antiplatelet therapy remains controversial. The aim of this study was to analyze data from a prospective registry of patients with ST-segment elevation myocardial infarctions admitted
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2014.04.029