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Spatially and spectrally resolved particle swarm optimization for precise optical property estimation using diffuse-reflectance spectroscopy

This paper presents a new approach to estimate optical properties (absorption and scattering coefficients µa and µs) of biological tissues from spatially-resolved spectroscopy measurements. A Particle Swarm Optimization (PSO)-based algorithm was implemented and firstly modified to deal with spatial...

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Bibliographic Details
Published in:Optics express 2016-06, Vol.24 (12), p.12682-12700
Main Authors: Kholodtsova, Maria N, Daul, Christian, Loschenov, Victor B, Blondel, Walter C P M
Format: Article
Language:English
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Summary:This paper presents a new approach to estimate optical properties (absorption and scattering coefficients µa and µs) of biological tissues from spatially-resolved spectroscopy measurements. A Particle Swarm Optimization (PSO)-based algorithm was implemented and firstly modified to deal with spatial and spectral resolutions of the data, and to solve the corresponding inverse problem. Secondly, the optimization was improved by fitting exponential decays to the two best points among all clusters of the "particles" randomly distributed all over the parameter space (µs, µa) of possible solutions. The consequent acceleration of all the groups of particles to the "best" curve leads to significant error decrease in the optical property estimation. The study analyzes the estimated optical property error as a function of the various PSO parameter combinations, and several performance criteria such as the cost-function error and the number of iterations in the algorithms proposed. The final one led to error values between ground truth and estimated values of µs and µa less than 6%.
ISSN:1094-4087
1094-4087
DOI:10.1364/OE.24.012682