Improved Method of S-Alkylation of 2-Mercaptobenzimidazole Derivatives with Trialkylphosphite

A new method of S-alkylation of 2-mercaptobenzimidazole derivatives has been developed by the condensation of these heterocycles with trialkylphosphite in the presence of phosphorus oxychloride giving the corresponding 2-S-alkylbenzimidazoles. The structure of the obtained products has been establis...

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Bibliographic Details
Published in:Asian journal of chemistry 2016, Vol.28 (6), p.1267-1269
Main Authors: El-Kihel, A., Zouitina, S., Guesmi, S., Ahbala, M., Bauchat, P., Biersack, B.
Format: Article
Language:English
Subjects:
Chemical Sciences
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Summary:A new method of S-alkylation of 2-mercaptobenzimidazole derivatives has been developed by the condensation of these heterocycles with trialkylphosphite in the presence of phosphorus oxychloride giving the corresponding 2-S-alkylbenzimidazoles. The structure of the obtained products has been established by spectroscopic data.
ISSN:0970-7077
1861-4728
0975-427X
1861-471X
DOI:10.14233/ajchem.2016.19647