Arterial spin labeling in clinical pediatric imaging

Abstract Arterial spin labeling (ASL) perfusion-weighted magnetic resonance imaging is the only approach that enables direct and non-invasive quantitative measurement of cerebral blood flow in the brain regions without administration of contrast material and without radiation. ASL is thus a promisin...

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Bibliographic Details
Published in:Diagnostic and interventional imaging 2016-02, Vol.97 (2), p.151-158
Main Authors: Proisy, M, Bruneau, B, Rozel, C, Tréguier, C, Chouklati, K, Riffaud, L, Darnault, P, Ferré, J.-C
Format: Article
Language:English
Subjects:
Arterial spin labeling
Bioengineering
Brain perfusion
Cerebral Angiography - methods
Cerebrovascular Circulation
Child
Children
Functional Neuroimaging - methods
Humans
Life Sciences
Magnetic Resonance Angiography
MRI
Radiology
Spin Labels
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Summary:Abstract Arterial spin labeling (ASL) perfusion-weighted magnetic resonance imaging is the only approach that enables direct and non-invasive quantitative measurement of cerebral blood flow in the brain regions without administration of contrast material and without radiation. ASL is thus a promising perfusion imaging method for assessing cerebral blood flow in the pediatric population. Concerning newborns, there are current limitations because of their smaller brain size and lower brain perfusion. This article reviews and illustrates the use of ASL in pediatric clinical practice and discusses emerging cerebral perfusion imaging applications for children due to the highly convenient implementation of the ASL sequence.
ISSN:2211-5684
2211-5684
DOI:10.1016/j.diii.2015.09.001