Hemispheric specificity for proprioception: Postural control of standing following right or left hemisphere damage during ankle tendon vibration

• Published in: Brain research 2015-11, Vol.1625, p.159-170
• Main Authors: Duclos, Noémie C, Maynard, Luc, Abbas, Djawad, Mesure, Serge
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Ankle - innervation; Biotechnology; Brain Injuries - etiology; Brain Injuries - physiopathology; Brain Injuries - therapy; Cognitive science; Female; Functional Laterality - physiology; Hemisphere; Humans; Life Sciences; Male; Middle Aged; Neurology; Neuroscience; Non-paretic limb; Postural Balance - physiology; Postural control; Posture; Proprioception; Proprioception - physiology; Stroke; Stroke - complications; Vibration; Vibration - therapeutic use
• ISSN: 0006-8993; 1872-6240; 0006-8993
• DOI: 10.1016/j.brainres.2015.08.043

Abstract Right brain damage (RBD) following stroke often causes significant postural instability. In standing (without vision), patients with RBD are more unstable than those with left brain damage (LBD). We hypothesised that this postural instability would relate to the cortical integration of proprioceptive afferents. The aim of this study was to use tendon vibration to investigate whether these changes were specific to the paretic or non-paretic limbs. 14 LBD, 12 RBD patients and 20 healthy subjects were included. Displacement of the Centre of Pressure (CoP) was recorded during quiet standing, then during 3 vibration conditions (80 Hz – 20 s): paretic limb, non-paretic limb (left and right limbs for control subjects) and bilateral. Vibration was applied separately to the peroneal and Achilles tendons. Mean antero-posterior position of the CoP, variability and velocity were calculated before (4 s), during and after (24 s) vibration. For all parameters, the strongest perturbation was during Achilles vibrations. The Achilles non-paretic condition induced a larger backward displacement than the Achilles paretic condition. This condition caused specific behaviour on the velocity: the LBD group was perturbed at the onset of the vibrations, but gradually recovered their stability; the RBD group was significantly perturbed thereafter. After bilateral Achilles vibration, RBD patients required the most time to restore initial posture. The reduction in use of information from the paretic limb may be a central strategy to deal with risk-of-fall situations such as during Achilles vibration. The postural behaviour is profoundly altered by lesions of the right hemisphere when proprioception is perturbed.