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Advances in surface plasmon resonance-based high throughput biochips

This article reviews our recent advances in surface plasmon resonance (SPR) based biochips. It includes four issues, which are the preparation and characterization of high quality gold film, the preparation and characterization of self-assembled monolayer (SAM), dynamics of DNA adsorption on SAMs, a...

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Bibliographic Details
Published in:Frontiers of physics 2009-12, Vol.4 (4), p.469-480
Main Authors: Zhang, San-jun, Berguiga, Lotfi, Elezgaray, Juan, Hugo, Nicolas, Li, Wen-xue, Roland, Thibault, Zeng, He-ping, Argoul, Francoise
Format: Article
Language:English
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Summary:This article reviews our recent advances in surface plasmon resonance (SPR) based biochips. It includes four issues, which are the preparation and characterization of high quality gold film, the preparation and characterization of self-assembled monolayer (SAM), dynamics of DNA adsorption on SAMs, and SPR-based microscopies. Numerous topics related to SPR, such as, the modeling of SPR by transmission matrix, effective medium theory, applications of SPR in biology, and SPR-based novel microscopies, are discussed. A novel electrochemical technique, which is extremely useful for the preparation and characterization of high quality SAMs, is also discussed.
ISSN:1673-3487
2095-0462
1673-3606
2095-0470
DOI:10.1007/s11467-009-0069-8