A Review of Gold and Silver Nanoparticle‐Based Colorimetric Sensing Assays

• Published in: Advanced engineering materials 2017-12, Vol.19 (12), p.n/a
• Main Authors: Sabela, Myalowenkosi, Balme, Sebastien, Bechelany, Mikhael, Janot, Jean‐Marc, Bisetty, Krishna
• Format: Article
• Language: English
• Subjects: Analytical chemistry; Chemical Sciences; colorimetric‐based methods aggregation; gold and silver nanoparticles; Material chemistry
• ISSN: 1438-1656; 1527-2648
• DOI: 10.1002/adem.201700270

The nanoparticle colorimetric‐based methods have been extensively used for rapid detection, however there are few limitations which can be kept under control or avoided by understanding the crucial parameters involved in these reactions. This review addresses the main parameters that influence colorimetric‐based methods and provides a rational classification of the current approaches, by focusing particularly on gold nanoparticles (AuNPs) and silver nanoparticles (AgNPs). The AgNP and AuNP‐based colorimetric assays can be very efficient and sensitive especially for biomolecule identification and for metal ion detection in environmental screening. Specifically, this review highlights the detection of metal ions through their coordination with nanoparticle stabilizing ligands. The review also addresses various approaches based on label‐free aptasensors to better understand their role as smart colorimetric sensing devices. This review addresses the main parameters that influence the nanoparticle colorimetric‐based methods for rapid detection of biomolecules and metal ion in environmental screening. It provides a rational classification of the current approaches by focusing particularly on gold and silver nanoparticles.