Loading…
Bis-15-crown-5-ether-pillar[5]arene K+‑Responsive Channels
An artificial selective K+ channel is formed from the supramolecular organization on bis(benzo-15-crown-5- ether-ureido)-pillar[5]arene compound. This channel achieves a selectivity of SK+/Na+ = 5 for an initial transport rate of k K+ = 3.2 × 10–3 s–1. The cation-file diffusion occurs via selectiv...
Saved in:
Published in: | Organic letters 2017-03, Vol.19 (6), p.1438-1441 |
---|---|
Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | An artificial selective K+ channel is formed from the supramolecular organization on bis(benzo-15-crown-5- ether-ureido)-pillar[5]arene compound. This channel achieves a selectivity of SK+/Na+ = 5 for an initial transport rate of k K+ = 3.2 × 10–3 s–1. The cation-file diffusion occurs via selective macrocyclic-filters anchored on inactive supporting pillar[5]arene relays. The sandwich-type binding geometry of the K+ cation by two 15-crown-5 moieties sites is a key feature influencing channel efficiency. |
---|---|
ISSN: | 1523-7060 1523-7052 |
DOI: | 10.1021/acs.orglett.7b00352 |