Incremental Value of 18F-Fluorocholine PET/CT in the Localization of Double Parathyroid Adenomas

ABSTRACTA 73-year-old man displaying primary hyperparathyroidism with severe hypercalcemia (Ca4.1 mmol/l, PTH > 600 pmol/l) was referred for preoperative localization of a parathyroid adenoma. Tc-pertechnetate and Tc-sestaMIBI dual tracer scintigraphy displayed a mild focal uptake in the projecti...

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Bibliographic Details
Published in:Clinical nuclear medicine 2017-03, Vol.42 (3), p.218-220
Main Authors: Lalire, Paul, Ly, Sang, Deguelte, Sophie, Patey, Martine, Morland, David
Format: Article
Language:English
Subjects:
Adenoma - diagnostic imaging
Aged
Bioengineering
Choline - analogs & derivatives
Humans
Life Sciences
Male
Nuclear medicine
Parathyroid Neoplasms - diagnostic imaging
Positron Emission Tomography Computed Tomography
Radiopharmaceuticals
Sodium Pertechnetate Tc 99m
Technetium Tc 99m Sestamibi
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Summary:ABSTRACTA 73-year-old man displaying primary hyperparathyroidism with severe hypercalcemia (Ca4.1 mmol/l, PTH > 600 pmol/l) was referred for preoperative localization of a parathyroid adenoma. Tc-pertechnetate and Tc-sestaMIBI dual tracer scintigraphy displayed a mild focal uptake in the projection of the right thyroid lobe with negative ultrasonography. F-Fluorocholine PET/CT was quickly performed considering this discrepancy and not only confirmed the scintigraphic findings but also revealed a second contralateral focus of increased uptake, both later confirmed by operative consideration (the two other parathyroid glands are considered normal by the surgeon), pathology, and intraoperative parathyroid hormone assessment.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0000000000001500