The effect of pH on the dynamics of natural membranes

. Pure phospholipids and membrane fragments from bacterial cells living under various conditions were studied against the influence of the surrounding acidity on the internal dynamics. For that we compared mean square displacements extracted from elastic incoherent neutron scattering data, measured...

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Bibliographic Details
Published in:The European physical journal. E, Soft matter and biological physics Soft matter and biological physics, 2018-02, Vol.41 (2), p.22-8, Article 22
Main Authors: Guiral, M., Neitzel, C., Salvador Castell, M., Martinez, N., Giudici-Orticoni, M. T., Peters, J.
Format: Article
Language:English
Subjects:
Acidithiobacillus - chemistry
Acidithiobacillus - physiology
Biological and Medical Physics
Biological Physics
Biophysics
Cell Membrane - chemistry
Complex Fluids and Microfluidics
Complex Systems
Condensed matter physics
Elastic scattering
Elasticity
Escherichia coli - chemistry
Escherichia coli - physiology
Fragments
Hydrogen-Ion Concentration
Lipids
Molecular Dynamics Simulation
Nanotechnology
Neutron scattering
Phase transitions
Phospholipids
Phospholipids - chemistry
Physics
Physics and Astronomy
Polymer Sciences
Regular Article
Soft and Granular Matter
Softness
Surfaces and Interfaces
Thin Films
Transition temperature
Wolinella - chemistry
Wolinella - physiology
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Summary:. Pure phospholipids and membrane fragments from bacterial cells living under various conditions were studied against the influence of the surrounding acidity on the internal dynamics. For that we compared mean square displacements extracted from elastic incoherent neutron scattering data, measured both at low and at neutral p H, of the phospholipids 1,2-dimyristoyl- sn -glycero-3-phosphocholine and of samples from neutralophilic and acidophilic micro-organisms (some being hyperthermophilic and others mesophilic). The lipids showed a slight shift in the phase transition temperature of about 4 degrees under p H variation and became slightly more mobile at lower p H. The membrane fragments not used to extreme acidic conditions were significantly more sensitive to variations in the p H values, whereas the acidophilic and -tolerant samples were much less influenced by this parameter. They presented the higher softness at low p H, which was closer to their native condition. Such findings might be a hint for adaptation mechanisms to different acidity conditions. Graphical abstract
ISSN:1292-8941
1292-895X
DOI:10.1140/epje/i2018-11630-y