Dépression résistante : les autres stratégies thérapeutiques

Non-selective and irreversible MAOI have become as third or fourth-line strategy for the management of treatment-resistant depression. Non-selective and irreversible MAOI requires careful monitoring of drug interactions and dietary restrictions. Nutritional supplements such as omega-3 have been foun...

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Published in:La Presse médicale (1983) 2016-03, Vol.45 (3), p.350-359
Main Authors: Saba, Ghassen, Nieto, Isabel, Bation, Rémy, Allaïli, Najib, Bennabi, Djamila, Moliere, Fanny, Richieri, Raphaëlle, Holtzmann, Jérôme, Bubrovszky, Maxime, Camus, Vincent, Charpeaud, Thomas, Courtet, Philippe, Courvoisier, Pierre, Haesebaert, Frédéric, Doumy, Olivier, El-Hage, Wissam, Garnier, Marion, d'Amato, Thierry, Bougerol, Thierry, Lançon, Christophe, Haffen, Emmanuel, Llorca, Pierre-Michel, Vaiva, Guillaume, Bellivier, Frank, Leboyer, Marion, Aouizerate, Bruno
Format: Article
Language:fre
Subjects:
Human health and pathology
Life Sciences
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Summary:Non-selective and irreversible MAOI have become as third or fourth-line strategy for the management of treatment-resistant depression. Non-selective and irreversible MAOI requires careful monitoring of drug interactions and dietary restrictions. Nutritional supplements such as omega-3 have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment. The glutamate antagonist ketamine has been found to produce beneficial effects in the management of treatment-resistant depression while administered alone. Dopamine and/or norepinephrine agonists, such as methylphenidate, modafinil or pramipexole, have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment.
ISSN:0755-4982
2213-0276
DOI:10.1016/j.lpm.2016.02.005