CMOS BQJ detector chip with integrated charge-amplifiers for fluorescence measurements

A CMOS buried quad-junction (BQJ) photodetector chip was designed for quantitative analysis in multi-labeling fluorescence detection applications. The chip integrates four-channel charge preamplifiers associated to the multi-output BQJ detector. The chip was tested for noise analysis and evaluation...

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Bibliographic Details
Published in:Sensors and actuators. B, Chemical Chemical, 2014-01, Vol.190, p.288-294
Main Authors: Courcier, Thierry, Goulart, Mariana, Pittet, Patrick, de Lima Monteiro, Davies W., Charette, Paul G., Aimez, Vincent, Lu, Guo-Neng
Format: Article
Language:English
Subjects:
APS
Buried quad junction
Engineering Sciences
Fluorescence
Photodetector
Quantum-dots
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Summary:A CMOS buried quad-junction (BQJ) photodetector chip was designed for quantitative analysis in multi-labeling fluorescence detection applications. The chip integrates four-channel charge preamplifiers associated to the multi-output BQJ detector. The chip was tested for noise analysis and evaluation of the amplifiers’ characteristics. It has a sensitivity of 21.2V/lxs at 555nm and a detectivity D* up to 3×1013cmHz1/2W−1. A test of the chip for a two-label fluorescence case was performed using a mixture of quantum dots in a priori unknown proportions. Good agreement was obtained between the modeled and measured results.
ISSN:0925-4005
1873-3077
DOI:10.1016/j.snb.2013.08.021