Predominance of healthcare-associated cases among episodes of community-onset bacteraemia due to extended-spectrum β-lactamase-producing enterobacteriaceae

Highlights • True community-acquired (CA) ESBL-PE bacteraemia is rare. • CA ESBL-PE bacteraemia identified in only 3.2% of patients. • Major risk factor for community-onset ESBL-PE infection is prior hospital stay ≥5 days in previous year. • Appropriate empirical regimen administered within 24 h in...

Full description

Saved in:
Bibliographic Details
Published in:International journal of antimicrobial agents 2017-01, Vol.49 (1), p.67-73
Main Authors: Zahar, Jean-Ralph, Lesprit, Philippe, Ruckly, Stephane, Eden, Aurelia, Hikombo, Hitoto, Bernard, Louis, Harbarth, Stephan, Timsit, Jean-François, Brun-Buisson, Christian
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Antibiotic appropriateness
Bacteraemia
Bacteremia - epidemiology
Bacteremia - microbiology
beta-Lactamases - secretion
Community-Acquired Infections - epidemiology
Community-Acquired Infections - microbiology
Cross Infection - microbiology
Enterobacteriaceae - classification
Enterobacteriaceae - enzymology
Enterobacteriaceae - isolation & purification
Enterobacteriaceae Infections - epidemiology
Enterobacteriaceae Infections - microbiology
Extended-spectrum β-lactamase
Female
Human health and pathology
Humans
Infectious Disease
Infectious diseases
Life Sciences
Male
Microbiology and Parasitology
Middle Aged
Pharmaceutical sciences
Pharmacology
Prevalence
Prospective Studies
Risk Factors
Survival Analysis
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Highlights • True community-acquired (CA) ESBL-PE bacteraemia is rare. • CA ESBL-PE bacteraemia identified in only 3.2% of patients. • Major risk factor for community-onset ESBL-PE infection is prior hospital stay ≥5 days in previous year. • Appropriate empirical regimen administered within 24 h in 45% of ESBL-PE bacteraemia patients. • Patients with CA ESBL-PE bacteraemia had a comparable outcome to those without ESBL-PE infection.
ISSN:0924-8579
1872-7913
DOI:10.1016/j.ijantimicag.2016.09.032