Fine particulate pollution and asthma exacerbations

ObjectiveAs the results from epidemiological studies about the impact of outdoor air pollution on asthma in children are heterogeneous, our objective was to investigate the association between asthma exacerbation in children and exposure to air pollutants.MethodsA database of 1 264 585 paediatric vi...

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Bibliographic Details
Published in:Archives of disease in childhood 2018-09, Vol.103 (9), p.828-831
Main Authors: Bouazza, Naïm, Foissac, Frantz, Urien, Saik, Guedj, Romain, Carbajal, Ricardo, Tréluyer, Jean-Marc, Chappuy, Hélène
Format: Article
Language:English
Subjects:
Age
Air pollution
Algorithms
Allergies
Asthma
Children
Data collection
Ecology, environment
Emergency medical care
Environmental Influences
Epidemiology
Health
Hospitals
Human health and pathology
Humidity
Life Sciences
Markov Processes
Molecular Biology
Nitrogen dioxide
Outdoor air quality
Particulate matter
Particulate pollution
Patients
Pediatrics
Pollen
Pollutants
Pollution
Postal codes
Precipitation
Pulmonology and respiratory tract
Respiratory syncytial virus
Santé publique et épidémiologie
Short term
Statistical Analysis
Systematic review
Viral infections
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Summary:ObjectiveAs the results from epidemiological studies about the impact of outdoor air pollution on asthma in children are heterogeneous, our objective was to investigate the association between asthma exacerbation in children and exposure to air pollutants.MethodsA database of 1 264 585 paediatric visits during the 2010–2015 period to the emergency rooms from 20 emergency departments (EDs) of ‘Assistance Publique Hôpitaux de Paris (APHP)’, the largest hospital group in Europe, was used. A total of 47 107 visits were classified as asthma exacerbations. Concentration of air pollutants (nitrogen dioxide, ozone, fine particulate matter (PM) with an aerodynamic diameter smaller than 10  µm (PM10) and 2.5 µm (PM2.5)), as well as meteorological data, evolution of respiratory syncytial virus infection and pollen exposition, were collected on an hourly or daily basis for the same period using institutional databases. To assess the association between air pollution and asthma, mixed-effects quasi-Poisson regression modelling was performed.ResultsThe only compound independently associated with ED visits for asthma was PM2.5 (P
ISSN:0003-9888
1468-2044
DOI:10.1136/archdischild-2017-312826