La syphilis à Montpellier de 2002 à 2011. Enquête dans le service de dermatologie du CHRU et au CDAG-CIDDIST

• Published in: Annales de dermatologie et de vénéréologie 2015-12, Vol.142 (12), p.742-750
• Main Authors: Amelot, Florence, Picot, Eric, Meusy, Arthur, Rousseau, Chloé, Brun, Michel, Guillot, Bernard
• Format: Article
• Language: fre
• Subjects: Dermatology; Human health and pathology; Life Sciences
• ISSN: 0151-9638
• DOI: 10.1016/j.annder.2015.07.008

BACKGROUND:In a context of resurgent syphilis in France since 2000, we conducted a retrospective study in two different centres in Montpellier, France: the dermatology department of a public hospital and an anonymous and free centre for provision of information, diagnosis and treatment of venereal diseases (CDAG-CIDDIST).PATIENTS AND METHODS:All patients with syphilis seen from January 2002 to December 2011 were included with the collaboration of the National Health Institute (InVS) and the Bacteriology Department of the public hospital. Epidemiology, clinical presentation, serological data, and treatment and monitoring data for up to 2 years were recorded.RESULTS:One hundred and seventy-five cases of syphilis were diagnosed: 154 at the CDAG and 21 at the dermatology unit. Ninety-six percent of cases concerned men with a median age of 36 years. Eighty-two percent of these cases involved men having sex with men (MSM). Forty-nine percent of cases were diagnosed in the secondary stage, 22% in the primary stage and 28% in the latent stage. The treatment administered in the majority of cases (73%) was benzathine-penicillin G. The numbers of patients showing incomplete follow-up were equal at both centres, with 31 patients (17.7%) failing to attend the follow-up visit. A decrease of at least 2 dilutions in VDRL score occurred in the year following treatment for 93 of 103 patients (90%). Patients managed at the dermatology department were older than their counterparts managed at the CDAG and exhibited more frequent cutaneous eruptions (58% vs. 3%, P