Guidance for the diagnosis of pulmonary embolism during pregnancy: Consensus and controversies

Pulmonary embolism (PE) is one of the leading causes of maternal mortality despite a low incidence of PE during pregnancy. Several challenges surround the diagnosis of PE in pregnant women and the existing clinical guidelines provide weak recommendations on selecting the appropriate investigations f...

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Bibliographic Details
Published in:Thrombosis research 2017-09, Vol.157, p.23-28
Main Authors: Wan, Tony, Skeith, Leslie, Karovitch, Alan, Rodger, Marc, Le Gal, Grégoire
Format: Article
Language:English
Subjects:
Aged
Cardiology and cardiovascular system
Consensus
Deep vein thrombosis
Female
Human health and pathology
Humans
Life Sciences
Pregnancy
Pulmonary embolism
Pulmonary Embolism - diagnosis
Pulmonary Embolism - pathology
Risk Factors
Venous thromboembolism
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Summary:Pulmonary embolism (PE) is one of the leading causes of maternal mortality despite a low incidence of PE during pregnancy. Several challenges surround the diagnosis of PE in pregnant women and the existing clinical guidelines provide weak recommendations on selecting the appropriate investigations for suspected PE in pregnancy. The purpose of this narrative review is to compare and contrast the recommendations of current clinical guidelines and review the evidence underpinning the recommendations on the evaluation of suspected PE in pregnancy. Consensus and controversies, knowledge gaps and areas requiring further research will be highlighted. •Pulmonary embolism (PE) is one of the leading causes of maternal mortality.•Clinical diagnosis is challenging: physiological changes, overlap with symptoms.•Current guidelines for investigations for suspected PE in pregnancy are inconsistent.•More research on pregnancy specific diagnostic algorithms is required.
ISSN:0049-3848
1879-2472
DOI:10.1016/j.thromres.2017.06.025