pH-Sensitive Interactions between Cellulose Nanocrystals and DOPC Liposomes

The interaction of 1,2 dioleolyl-sn-glycero-3-phosphatidylcholine (DOPC) vesicles with cellulose nanocrystals (CNCs) using several complementary techniques. Dynamic light scattering, zeta-potential, cryo-transmission electron microscopy and isothermal titration calorimetry (ITC) analyses confirmed t...

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Bibliographic Details
Published in:Biomacromolecules 2017-09, Vol.18 (9), p.2918-2927
Main Authors: Navon, Yotam, Radavidson, Harisoa, Putaux, Jean-Luc, Jean, Bruno, Heux, Laurent
Format: Article
Language:English
Subjects:
Cellulose - chemistry
Chemical Sciences
Hydrogen-Ion Concentration
Liposomes - chemistry
Nanoparticles - chemistry
Phosphatidylcholines - chemistry
Polymers
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Summary:The interaction of 1,2 dioleolyl-sn-glycero-3-phosphatidylcholine (DOPC) vesicles with cellulose nanocrystals (CNCs) using several complementary techniques. Dynamic light scattering, zeta-potential, cryo-transmission electron microscopy and isothermal titration calorimetry (ITC) analyses confirmed the formation of pH-dependent CNC–liposome complexes. ITC was used to characterize the thermodynamic properties of this interaction. Positive values of enthalpy were found at pH lower than 5 where the charge sign of the constituents was opposite. The association was more pronounced at lower pH, as indicated by the higher values of association constant. We suggest that the positive enthalpy is derived from the release of counterions from the particle hydration shell during the association and that the charge of the vesicles plays a significant role in this interaction.
ISSN:1525-7797
1526-4602
DOI:10.1021/acs.biomac.7b00872