MaxSynBio: Avenues Towards Creating Cells from the Bottom Up

A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom‐up approach to synthetic biology. MaxSynBio focuses on the detailed analysis an...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2018-10, Vol.57 (41), p.13382-13392
Main Authors: Schwille, Petra, Spatz, Joachim, Landfester, Katharina, Bodenschatz, Eberhard, Herminghaus, Stephan, Sourjik, Victor, Erb, Tobias J., Bastiaens, Philippe, Lipowsky, Reinhard, Hyman, Anthony, Dabrock, Peter, Baret, Jean‐Christophe, Vidakovic‐Koch, Tanja, Bieling, Peter, Dimova, Rumiana, Mutschler, Hannes, Robinson, Tom, Tang, T.‐Y. Dora, Wegner, Seraphine, Sundmacher, Kai
Format: Article
Language:English
Subjects:
Biotechnology
bottom-up design
Chemical Sciences
Condensed Matter
Consortia
Life Sciences
Material chemistry
microfluidics
Modular construction
Physics
protocells
synthetic biology
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Summary:A large German research consortium mainly within the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program of MaxSynBio relies solely on the bottom‐up approach to synthetic biology. MaxSynBio focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non‐living components. The fundamental insights gained from the activities in MaxSynBio could eventually be utilized for establishing a new generation of biotechnological processes, which would be based on synthetic cell constructs that replace the natural cells currently used in conventional biotechnology. To the Max: A research consortium associated with the Max Planck Society (“MaxSynBio”) was formed to investigate living systems from a fundamental perspective. The research program relies solely on the bottom‐up approach and focuses on the detailed analysis and understanding of essential processes of life through modular reconstitution in minimal synthetic systems. The ultimate goal is to construct a basic living unit entirely from non‐living components.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201802288