Quest for novel fluorogenic xanthene dyes: Synthesis, spectral properties and stability of 3-imino-3H-xanthen-6-amine (pyronin) and its silicon analog

[Display omitted] •The synthesis of 3-imino-3H-xanthene-6-amine dye (pyronin) was revisited.•The orange-red emitting silicon analog (Si-pyronin) was prepared for the first time.•Both compounds exhibit outstanding fluorescence properties in aqueous solution.•Aqueous stability of fluorogenic Si-pyroni...

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Published in:Tetrahedron letters 2018-12, Vol.59 (52), p.4574-4581
Main Authors: Romieu, Anthony, Dejouy, Garance, Valverde, Ibai E.
Format: Article
Language:English
Subjects:
Amino group protection-deprotection
Chemical Sciences
Fluorescent probe
Hetero-xanthene dye
Organic chemistry
Protease
Pyronin
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cited_by cdi_FETCH-LOGICAL-c452t-3c8690a001e91a22af65a253dfc1a1d6dcbcc4d57e691dc3676d91e5182091e43
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description [Display omitted] •The synthesis of 3-imino-3H-xanthene-6-amine dye (pyronin) was revisited.•The orange-red emitting silicon analog (Si-pyronin) was prepared for the first time.•Both compounds exhibit outstanding fluorescence properties in aqueous solution.•Aqueous stability of fluorogenic Si-pyronin dye only at pH 
doi_str_mv 10.1016/j.tetlet.2018.11.031
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ispartof Tetrahedron letters, 2018-12, Vol.59 (52), p.4574-4581
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source ScienceDirect Freedom Collection 2022-2024
subjects Amino group protection-deprotection
Chemical Sciences
Fluorescent probe
Hetero-xanthene dye
Organic chemistry
Protease
Pyronin
title Quest for novel fluorogenic xanthene dyes: Synthesis, spectral properties and stability of 3-imino-3H-xanthen-6-amine (pyronin) and its silicon analog
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