Identification of Ras, Pten and p70S6K homologs in the Pacific oyster Crassostrea gigas and diet control of insulin pathway

Highlights ► This paper tells about the involvement of insulin pathway in Crassostrea gigas . ► Identification of effectors of this pathway (Ras, Pten, p70S6K) has been performed. ► The link between storage and gametogenesis is studied with laser microdissection. ► Effect of diet in insulin-like reg...

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Bibliographic Details
Published in:General and comparative endocrinology 2012-03, Vol.176 (1), p.28-38
Main Authors: Jouaux, A, Franco, A, Heude-Berthelin, C, Sourdaine, P, Blin, J.L, Mathieu, M, Kellner, K
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animal Feed
Animals
Crassostrea - genetics
Crassostrea - metabolism
Crassostrea gigas
Dietary restriction
Endocrinology & Metabolism
Environment
environmental factors
Female
food deprivation
Food Deprivation - physiology
Gonads - physiology
Insulin
Insulin - metabolism
Life Sciences
Male
metabolism
Molecular Sequence Data
oysters
p70S6K
Pten
PTEN Phosphohydrolase - genetics
PTEN Phosphohydrolase - metabolism
Ras
ras Proteins - genetics
ras Proteins - metabolism
Ribosomal Protein S6 Kinases, 70-kDa - genetics
Ribosomal Protein S6 Kinases, 70-kDa - metabolism
Sequence Homology, Amino Acid
Signal Transduction - physiology
transcriptional activation
Transcriptional Activation - physiology
vertebrates
vitellogenesis
Vitellogenesis - physiology
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Summary:Highlights ► This paper tells about the involvement of insulin pathway in Crassostrea gigas . ► Identification of effectors of this pathway (Ras, Pten, p70S6K) has been performed. ► The link between storage and gametogenesis is studied with laser microdissection. ► Effect of diet in insulin-like regulation has been studied on reproductive strategy. ► This study takes into account the seasonal reproductive cycle.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2011.12.008