Outcomes and Predictive Factors After Cataract Surgery in Patients With Neovascular Age-related Macular Degeneration. The Fight Retinal Blindness! Project

To evaluate outcomes and predictive factors of visual acuity (VA) change after cataract surgery in patients being treated for neovascular age-related macular degeneration (nAMD). Retrospective, matched case-control study. We studied eyes undergoing cataract surgery that had been tracked since they f...

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Bibliographic Details
Published in:American journal of ophthalmology 2018-06, Vol.190, p.50-57
Main Authors: Daien, Vincent, Nguyen, Vuong, Morlet, Nigel, Arnold, Jennifer J., Essex, Rohan W., Young, Stephanie, Hunyor, Alex, Gillies, Mark C., Barthelmes, Daniel, Squirrel, D., Field, A., Dayajeewa, C., Essex, R., Dunlop, A., Young, S., Guymer, R., Chow, L., Amini, A., Windle, P., Gillies, M., Chen, J., Perks, M., Saha, N., Phillips, R., Lake, S., Lal, S., Arnold, J., Fraser-Bell, S., Barnes, R., Swamy, B., Barthelmes, D., Day, J.O', Cohn, A.
Format: Article
Language:English
Subjects:
Age
Aged
Angiogenesis Inhibitors - therapeutic use
Case-Control Studies
Cataract Extraction
Cataracts
Choroidal Neovascularization - drug therapy
Choroidal Neovascularization - physiopathology
Ethics
Eye surgery
Female
Human health and pathology
Humans
Intravitreal Injections
Life Sciences
Macular degeneration
Male
Ophthalmology
Pseudophakia - physiopathology
Retrospective Studies
Treatment Outcome
Vascular endothelial growth factor
Vascular Endothelial Growth Factor A - antagonists & inhibitors
Visual Acuity - physiology
Wet Macular Degeneration - drug therapy
Wet Macular Degeneration - physiopathology
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Summary:To evaluate outcomes and predictive factors of visual acuity (VA) change after cataract surgery in patients being treated for neovascular age-related macular degeneration (nAMD). Retrospective, matched case-control study. We studied eyes undergoing cataract surgery that had been tracked since they first started treatment for nAMD. These eyes were compared with a cohort of unoperated phakic eyes being treated for nAMD (3 per case) matched for treatment duration before cataract surgery, baseline VA, age, and length of follow-up. We included 124 patients that had cataract surgery and 372 matched controls. The mean (95% confidence interval) VA gained was 10.6 letters (7.8, 13.2; P 
ISSN:0002-9394
1879-1891
DOI:10.1016/j.ajo.2018.03.012