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Selection of lymph node target volumes for definitive head and neck radiation therapy: a 2019 Update
•Updated proposal for the selection of nodal target volumes in definitive radiotherapy is provided.•Recommendations for both negative and positive neck are provided.•The locations addressed are: oral cavity, oropharynx, hypopharynx, larynx, nasopharynx, paranasal sinuses, nasal cavity and carcinoma...
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Published in: | Radiotherapy and oncology 2019-05, Vol.134, p.1-9 |
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Main Authors: | , , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | •Updated proposal for the selection of nodal target volumes in definitive radiotherapy is provided.•Recommendations for both negative and positive neck are provided.•The locations addressed are: oral cavity, oropharynx, hypopharynx, larynx, nasopharynx, paranasal sinuses, nasal cavity and carcinoma of unknown primary.•Recommendations are according to the latest neck node level terminology and staging.
In 2000, a panel of experts published a proposal for the selection of lymph node target volumes for definitive head and neck radiation therapy (Radiother Oncol, 2000; 56: 135–150). Hereunder, this selection is updated and extended to also cover primary sites not previously covered.
The lymphatic spread of head and neck cancers into neck lymph nodes was comprehensively reviewed based on radiological, surgical and pathological literature regarding both initial involvement and patterns of failure. Then a panel of worldwide head and neck radiotherapy experts agreed on a consensus for the selection of both high- and low-risk lymph node target volumes for the node negative and the node positive neck.
An updated selection of lymph node target volumes is reported for oral cavity, oropharynx, hypopharynx, larynx, nasopharynx, paranasal sinuses, nasal cavity and carcinoma of unknown primary as a function of the nodal staging (UICC 8th edition).
The selection of lymph node target volumes for head and neck cancers treated with IMRT/VMAT or other highly conformal techniques (e.g. proton therapy) requires a rigorous approach. This updated proposal of selection should help clinicians for the selection of lymph nodes target volumes and contribute to increase consistency. |
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ISSN: | 0167-8140 1879-0887 |
DOI: | 10.1016/j.radonc.2019.01.018 |